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The Peptidic GHS-R antagonist [D-Lys(3)]GHRP-6 markedly improves adiposity and related metabolic abnormalities in a mouse model of postmenopausal obesity.
Maletínská L, Matyšková R, Maixnerová J, Sýkora D, Pýchová M, Spolcová A, Blechová M, Drápalová J, Lacinová Z, Haluzík M, Zelezná B. Maletínská L, et al. Among authors: sykora d. Mol Cell Endocrinol. 2011 Aug 22;343(1-2):55-62. doi: 10.1016/j.mce.2011.06.006. Epub 2011 Jun 17. Mol Cell Endocrinol. 2011. PMID: 21704671
Ghrelin agonist JMV 1843 increases food intake, body weight and expression of orexigenic neuropeptides in mice.
Holubová M, Spolcová A, Demianová Z, Sýkora D, Fehrentz JA, Martinez J, Stofková A, Jurčovičová J, Drápalová J, Lacinová Z, Haluzík M, Zelezná B, Maletínská L. Holubová M, et al. Among authors: sykora d. Physiol Res. 2013;62(4):435-44. doi: 10.33549/physiolres.932488. Epub 2013 Apr 16. Physiol Res. 2013. PMID: 23590608 Free article.
Triazole GHS-R1a antagonists JMV4208 and JMV3002 attenuate food intake, body weight, and adipose tissue mass in mice.
Holubová M, Nagelová V, Lacinová Z, Haluzík M, Sýkora D, Moulin A, Blayo AL, Fehrentz JA, Martinez J, Stofkova A, Jurčovičová J, Zelezná B, Maletínská L. Holubová M, et al. Among authors: sykora d. Mol Cell Endocrinol. 2014 Aug 5;393(1-2):120-8. doi: 10.1016/j.mce.2014.06.003. Epub 2014 Jun 20. Mol Cell Endocrinol. 2014. PMID: 24953973
Novel lipidized analogs of prolactin-releasing peptide have prolonged half-lives and exert anti-obesity effects after peripheral administration.
Maletínská L, Nagelová V, Tichá A, Zemenová J, Pirník Z, Holubová M, Špolcová A, Mikulášková B, Blechová M, Sýkora D, Lacinová Z, Haluzík M, Železná B, Kuneš J. Maletínská L, et al. Among authors: sykora d. Int J Obes (Lond). 2015 Jun;39(6):986-93. doi: 10.1038/ijo.2015.28. Epub 2015 Mar 16. Int J Obes (Lond). 2015. PMID: 25771926
Urinary metabolomic profiling in mice with diet-induced obesity and type 2 diabetes mellitus after treatment with metformin, vildagliptin and their combination.
Pelantová H, Bugáňová M, Holubová M, Šedivá B, Zemenová J, Sýkora D, Kaválková P, Haluzík M, Železná B, Maletínská L, Kuneš J, Kuzma M. Pelantová H, et al. Among authors: sykora d. Mol Cell Endocrinol. 2016 Aug 15;431:88-100. doi: 10.1016/j.mce.2016.05.003. Epub 2016 May 7. Mol Cell Endocrinol. 2016. PMID: 27164444
97 results