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Antivirulence Bispecific Monoclonal Antibody-Mediated Protection against Pseudomonas aeruginosa Ventilator-Associated Pneumonia in a Rabbit Model.
Aguiar-Alves F, Le HN, Tran VG, Gras E, Vu TTT, Dong OX, Quetz JS, Cheng LI, Yu L, Sellman BR, Stover CK, DiGiandomenico A, Diep BA. Aguiar-Alves F, et al. Among authors: cheng li. Antimicrob Agents Chemother. 2022 Feb 15;66(2):e0202221. doi: 10.1128/AAC.02022-21. Epub 2021 Dec 13. Antimicrob Agents Chemother. 2022. PMID: 34902264 Free PMC article.
Assessment of an anti-alpha-toxin monoclonal antibody for prevention and treatment of Staphylococcus aureus-induced pneumonia.
Hua L, Hilliard JJ, Shi Y, Tkaczyk C, Cheng LI, Yu X, Datta V, Ren S, Feng H, Zinsou R, Keller A, O'Day T, Du Q, Cheng L, Damschroder M, Robbie G, Suzich J, Stover CK, Sellman BR. Hua L, et al. Among authors: cheng l, cheng li. Antimicrob Agents Chemother. 2014;58(2):1108-17. doi: 10.1128/AAC.02190-13. Epub 2013 Dec 2. Antimicrob Agents Chemother. 2014. PMID: 24295977 Free PMC article.
Targeting Alpha Toxin To Mitigate Its Lethal Toxicity in Ferret and Rabbit Models of Staphylococcus aureus Necrotizing Pneumonia.
Diep BA, Hilliard JJ, Le VT, Tkaczyk C, Le HN, Tran VG, Rao RL, Dip EC, Pereira-Franchi EP, Cha P, Jacobson S, Broome R, Cheng LI, Weiss W, Prokai L, Nguyen V, Stover CK, Sellman BR. Diep BA, et al. Among authors: cheng li. Antimicrob Agents Chemother. 2017 Mar 24;61(4):e02456-16. doi: 10.1128/AAC.02456-16. Print 2017 Apr. Antimicrob Agents Chemother. 2017. PMID: 28115346 Free PMC article.
Mouse model of hematogenous implant-related Staphylococcus aureus biofilm infection reveals therapeutic targets.
Wang Y, Cheng LI, Helfer DR, Ashbaugh AG, Miller RJ, Tzomides AJ, Thompson JM, Ortines RV, Tsai AS, Liu H, Dillen CA, Archer NK, Cohen TS, Tkaczyk C, Stover CK, Sellman BR, Miller LS. Wang Y, et al. Among authors: cheng li. Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5094-E5102. doi: 10.1073/pnas.1703427114. Epub 2017 Jun 12. Proc Natl Acad Sci U S A. 2017. PMID: 28607050 Free PMC article.
An engineered bispecific DNA-encoded IgG antibody protects against Pseudomonas aeruginosa in a pneumonia challenge model.
Patel A, DiGiandomenico A, Keller AE, Smith TRF, Park DH, Ramos S, Schultheis K, Elliott STC, Mendoza J, Broderick KE, Wise MC, Yan J, Jiang J, Flingai S, Khan AS, Muthumani K, Humeau L, Cheng LI, Wachter-Rosati L, Stover CK, Sardesai NY, Weiner DB. Patel A, et al. Among authors: cheng li. Nat Commun. 2017 Sep 21;8(1):637. doi: 10.1038/s41467-017-00576-7. Nat Commun. 2017. PMID: 28935938 Free PMC article.
Neutralizing Alpha-Toxin Accelerates Healing of Staphylococcus aureus-Infected Wounds in Nondiabetic and Diabetic Mice.
Ortines RV, Liu H, Cheng LI, Cohen TS, Lawlor H, Gami A, Wang Y, Dillen CA, Archer NK, Miller RJ, Ashbaugh AG, Pinsker BL, Marchitto MC, Tkaczyk C, Stover CK, Sellman BR, Miller LS. Ortines RV, et al. Among authors: cheng li. Antimicrob Agents Chemother. 2018 Feb 23;62(3):e02288-17. doi: 10.1128/AAC.02288-17. Print 2018 Mar. Antimicrob Agents Chemother. 2018. PMID: 29311091 Free PMC article.
Neutrophil Extracellular Traps Confine Pseudomonas aeruginosa Ocular Biofilms and Restrict Brain Invasion.
Thanabalasuriar A, Scott BNV, Peiseler M, Willson ME, Zeng Z, Warrener P, Keller AE, Surewaard BGJ, Dozier EA, Korhonen JT, Cheng LI, Gadjeva M, Stover CK, DiGiandomenico A, Kubes P. Thanabalasuriar A, et al. Among authors: cheng li. Cell Host Microbe. 2019 Apr 10;25(4):526-536.e4. doi: 10.1016/j.chom.2019.02.007. Epub 2019 Mar 28. Cell Host Microbe. 2019. PMID: 30930127 Free PMC article.
PD-L1+ neutrophils contribute to injury-induced infection susceptibility.
Thanabalasuriar A, Chiang AJ, Morehouse C, Camara M, Hawkins S, Keller AE, Koksal AC, Caceres CS, Berlin AA, Holoweckyj N, Takahashi VN, Cheng L, de Los Reyes M, Pelletier M, Patera AC, Sellman B, Hess S, Marelli M, Boo CC, Cohen TS, DiGiandomenico A. Thanabalasuriar A, et al. Sci Adv. 2021 Mar 5;7(10):eabd9436. doi: 10.1126/sciadv.abd9436. Print 2021 Mar. Sci Adv. 2021. PMID: 33674305 Free PMC article.
Multimechanistic Monoclonal Antibody Combination Targeting Key Staphylococcus aureus Virulence Determinants in a Rabbit Model of Prosthetic Joint Infection.
Mao Y, Valour F, Nguyen NTQ, Doan TMN, Koelkebeck H, Richardson C, Cheng LI, Sellman BR, Tkaczyk C, Diep BA. Mao Y, et al. Among authors: cheng li. Antimicrob Agents Chemother. 2021 Jun 17;65(7):e0183220. doi: 10.1128/AAC.01832-20. Epub 2021 Jun 17. Antimicrob Agents Chemother. 2021. PMID: 33903108 Free PMC article.
T follicular helper-like cells contribute to skin fibrosis.
Taylor DK, Mittereder N, Kuta E, Delaney T, Burwell T, Dacosta K, Zhao W, Cheng LI, Brown C, Boutrin A, Guo X, White WI, Zhu J, Dong H, Bowen MA, Lin J, Gao C, Yu L, Ramaswamy M, Gaudreau MC, Woods R, Herbst R, Carlesso G. Taylor DK, et al. Among authors: cheng li. Sci Transl Med. 2018 Mar 7;10(431):eaaf5307. doi: 10.1126/scitranslmed.aaf5307. Sci Transl Med. 2018. PMID: 29514998
3,630 results