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Antivirulence Bispecific Monoclonal Antibody-Mediated Protection against Pseudomonas aeruginosa Ventilator-Associated Pneumonia in a Rabbit Model.
Aguiar-Alves F, Le HN, Tran VG, Gras E, Vu TTT, Dong OX, Quetz JS, Cheng LI, Yu L, Sellman BR, Stover CK, DiGiandomenico A, Diep BA. Aguiar-Alves F, et al. Among authors: yu l. Antimicrob Agents Chemother. 2022 Feb 15;66(2):e0202221. doi: 10.1128/AAC.02022-21. Epub 2021 Dec 13. Antimicrob Agents Chemother. 2022. PMID: 34902264 Free PMC article.
Staphylococcus aureus Alpha-Toxin Is Conserved among Diverse Hospital Respiratory Isolates Collected from a Global Surveillance Study and Is Neutralized by Monoclonal Antibody MEDI4893.
Tabor DE, Yu L, Mok H, Tkaczyk C, Sellman BR, Wu Y, Oganesyan V, Slidel T, Jafri H, McCarthy M, Bradford P, Esser MT. Tabor DE, et al. Among authors: yu l. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5312-21. doi: 10.1128/AAC.00357-16. Print 2016 Sep. Antimicrob Agents Chemother. 2016. PMID: 27324766 Free PMC article.
Mouse model of Gram-negative prosthetic joint infection reveals therapeutic targets.
Thompson JM, Miller RJ, Ashbaugh AG, Dillen CA, Pickett JE, Wang Y, Ortines RV, Sterling RS, Francis KP, Bernthal NM, Cohen TS, Tkaczyk C, Yu L, Stover CK, DiGiandomenico A, Sellman BR, Thorek DL, Miller LS. Thompson JM, et al. Among authors: yu l. JCI Insight. 2018 Sep 6;3(17):e121737. doi: 10.1172/jci.insight.121737. eCollection 2018 Sep 6. JCI Insight. 2018. PMID: 30185667 Free PMC article.
Phase 1 study of MEDI3902, an investigational anti-Pseudomonas aeruginosa PcrV and Psl bispecific human monoclonal antibody, in healthy adults.
Ali SO, Yu XQ, Robbie GJ, Wu Y, Shoemaker K, Yu L, DiGiandomenico A, Keller AE, Anude C, Hernandez-Illas M, Bellamy T, Falloon J, Dubovsky F, Jafri HS. Ali SO, et al. Among authors: yu l, yu xq. Clin Microbiol Infect. 2019 May;25(5):629.e1-629.e6. doi: 10.1016/j.cmi.2018.08.004. Epub 2018 Aug 11. Clin Microbiol Infect. 2019. PMID: 30107283 Free article. Clinical Trial.
Associations of pathogen-specific and host-specific characteristics with disease outcome in patients with Staphylococcus aureus bacteremic pneumonia.
Sharma-Kuinkel BK, Tkaczyk C, Bonnell J, Yu L, Tovchigrechko A, Tabor DE, Park LP, Ruffin F, Esser MT, Sellman BR, Fowler VG Jr, Ruzin A. Sharma-Kuinkel BK, et al. Among authors: yu l. Clin Transl Immunology. 2019 Jul 19;8(7):e01070. doi: 10.1002/cti2.1070. eCollection 2019. Clin Transl Immunology. 2019. PMID: 31360464 Free PMC article.
Characterization of alpha-toxin hla gene variants, alpha-toxin expression levels, and levels of antibody to alpha-toxin in hemodialysis and postsurgical patients with Staphylococcus aureus bacteremia.
Sharma-Kuinkel BK, Wu Y, Tabor DE, Mok H, Sellman BR, Jenkins A, Yu L, Jafri HS, Rude TH, Ruffin F, Schell WA, Park LP, Yan Q, Thaden JT, Messina JA, Fowler VG Jr, Esser MT. Sharma-Kuinkel BK, et al. Among authors: yu l. J Clin Microbiol. 2015 Jan;53(1):227-36. doi: 10.1128/JCM.02023-14. Epub 2014 Nov 12. J Clin Microbiol. 2015. PMID: 25392350 Free PMC article.
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