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Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma.
Lu X, Sabbasani VR, Osei-Amponsa V, Evans CN, King JC, Tarasov SG, Dyba M, Das S, Chan KC, Schwieters CD, Choudhari S, Fromont C, Zhao Y, Tran B, Chen X, Matsuo H, Andresson T, Chari R, Swenson RE, Tarasova NI, Walters KJ. Lu X, et al. Among authors: dyba m. Nat Commun. 2021 Dec 16;12(1):7318. doi: 10.1038/s41467-021-27570-4. Nat Commun. 2021. PMID: 34916494 Free PMC article.
Engineered human antibody constant domains with increased stability.
Gong R, Vu BK, Feng Y, Prieto DA, Dyba MA, Walsh JD, Prabakaran P, Veenstra TD, Tarasov SG, Ishima R, Dimitrov DS. Gong R, et al. J Biol Chem. 2009 May 22;284(21):14203-10. doi: 10.1074/jbc.M900769200. Epub 2009 Mar 23. J Biol Chem. 2009. PMID: 19307178 Free PMC article.
An unusual topological structure of the HIV-1 Rev response element.
Fang X, Wang J, O'Carroll IP, Mitchell M, Zuo X, Wang Y, Yu P, Liu Y, Rausch JW, Dyba MA, Kjems J, Schwieters CD, Seifert S, Winans RE, Watts NR, Stahl SJ, Wingfield PT, Byrd RA, Le Grice SF, Rein A, Wang YX. Fang X, et al. Among authors: dyba ma. Cell. 2013 Oct 24;155(3):594-605. doi: 10.1016/j.cell.2013.10.008. Epub 2013 Oct 24. Cell. 2013. PMID: 24243017 Free PMC article.
GTP-Dependent K-Ras Dimerization.
Muratcioglu S, Chavan TS, Freed BC, Jang H, Khavrutskii L, Freed RN, Dyba MA, Stefanisko K, Tarasov SG, Gursoy A, Keskin O, Tarasova NI, Gaponenko V, Nussinov R. Muratcioglu S, et al. Structure. 2015 Jul 7;23(7):1325-35. doi: 10.1016/j.str.2015.04.019. Epub 2015 Jun 4. Structure. 2015. PMID: 26051715 Free PMC article.
Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.
Stagno JR, Liu Y, Bhandari YR, Conrad CE, Panja S, Swain M, Fan L, Nelson G, Li C, Wendel DR, White TA, Coe JD, Wiedorn MO, Knoska J, Oberthuer D, Tuckey RA, Yu P, Dyba M, Tarasov SG, Weierstall U, Grant TD, Schwieters CD, Zhang J, Ferré-D'Amaré AR, Fromme P, Draper DE, Liang M, Hunter MS, Boutet S, Tan K, Zuo X, Ji X, Barty A, Zatsepin NA, Chapman HN, Spence JC, Woodson SA, Wang YX. Stagno JR, et al. Among authors: dyba m. Nature. 2017 Jan 12;541(7636):242-246. doi: 10.1038/nature20599. Epub 2016 Nov 14. Nature. 2017. PMID: 27841871 Free PMC article.
Covalent Rpn13-Binding Inhibitors for the Treatment of Ovarian Cancer.
Anchoori RK, Jiang R, Peng S, Soong RS, Algethami A, Rudek MA, Anders N, Hung CF, Chen X, Lu X, Kayode O, Dyba M, Walters KJ, Roden RBS. Anchoori RK, et al. Among authors: dyba m. ACS Omega. 2018 Sep 30;3(9):11917-11929. doi: 10.1021/acsomega.8b01479. Epub 2018 Sep 27. ACS Omega. 2018. PMID: 30288466 Free PMC article.
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