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Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma.
Lu X, Sabbasani VR, Osei-Amponsa V, Evans CN, King JC, Tarasov SG, Dyba M, Das S, Chan KC, Schwieters CD, Choudhari S, Fromont C, Zhao Y, Tran B, Chen X, Matsuo H, Andresson T, Chari R, Swenson RE, Tarasova NI, Walters KJ. Lu X, et al. Among authors: tarasov sg. Nat Commun. 2021 Dec 16;12(1):7318. doi: 10.1038/s41467-021-27570-4. Nat Commun. 2021. PMID: 34916494 Free PMC article.
Transmembrane inhibitors of P-glycoprotein, an ABC transporter.
Tarasova NI, Seth R, Tarasov SG, Kosakowska-Cholody T, Hrycyna CA, Gottesman MM, Michejda CJ. Tarasova NI, et al. Among authors: tarasov sg. J Med Chem. 2005 Jun 2;48(11):3768-75. doi: 10.1021/jm049065t. J Med Chem. 2005. PMID: 15916428
Engineered human antibody constant domains with increased stability.
Gong R, Vu BK, Feng Y, Prieto DA, Dyba MA, Walsh JD, Prabakaran P, Veenstra TD, Tarasov SG, Ishima R, Dimitrov DS. Gong R, et al. Among authors: tarasov sg. J Biol Chem. 2009 May 22;284(21):14203-10. doi: 10.1074/jbc.M900769200. Epub 2009 Mar 23. J Biol Chem. 2009. PMID: 19307178 Free PMC article.
Mechanisms of unphosphorylated STAT3 transcription factor binding to DNA.
Timofeeva OA, Chasovskikh S, Lonskaya I, Tarasova NI, Khavrutskii L, Tarasov SG, Zhang X, Korostyshevskiy VR, Cheema A, Zhang L, Dakshanamurthy S, Brown ML, Dritschilo A. Timofeeva OA, et al. Among authors: tarasov sg. J Biol Chem. 2012 Apr 20;287(17):14192-200. doi: 10.1074/jbc.M111.323899. Epub 2012 Feb 29. J Biol Chem. 2012. PMID: 22378781 Free PMC article.
GTP-Dependent K-Ras Dimerization.
Muratcioglu S, Chavan TS, Freed BC, Jang H, Khavrutskii L, Freed RN, Dyba MA, Stefanisko K, Tarasov SG, Gursoy A, Keskin O, Tarasova NI, Gaponenko V, Nussinov R. Muratcioglu S, et al. Among authors: tarasov sg. Structure. 2015 Jul 7;23(7):1325-35. doi: 10.1016/j.str.2015.04.019. Epub 2015 Jun 4. Structure. 2015. PMID: 26051715 Free PMC article.
42 results