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Discovery of Imidazole-Based Inhibitors of Plasmodium falciparum cGMP-Dependent Protein Kinase.
Bheemanaboina RRY, de Souza ML, Gonzalez ML, Mahmood SU, Eck T, Kreiss T, Aylor SO, Roth A, Lee P, Pybus BS, Colussi DJ, Childers WE, Gordon J, Siekierka JJ, Bhanot P, Rotella DP. Bheemanaboina RRY, et al. Among authors: de souza ml. ACS Med Chem Lett. 2021 Nov 15;12(12):1962-1967. doi: 10.1021/acsmedchemlett.1c00540. eCollection 2021 Dec 9. ACS Med Chem Lett. 2021. PMID: 34917261 Free PMC article.
Structure-Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials.
Gilleran JA, Ashraf K, Delvillar M, Eck T, Fondekar R, Miller EB, Hutchinson A, Dong A, Seitova A, De Souza ML, Augeri D, Halabelian L, Siekierka J, Rotella DP, Gordon J, Childers WE, Grier MC, Staker BL, Roberge JY, Bhanot P. Gilleran JA, et al. Among authors: de souza ml. J Med Chem. 2024 Mar 14;67(5):3467-3503. doi: 10.1021/acs.jmedchem.3c01795. Epub 2024 Feb 19. J Med Chem. 2024. PMID: 38372781
Correction to "Structure-Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials".
Gilleran JA, Ashraf K, Delvillar M, Eck T, Fondekar R, Miller EB, Hutchinson A, Dong A, Seitova A, De Souza ML, Augeri D, Halabelian L, Siekierka J, Rotella DP, Gordon J, Childers WE, Grier MC, Staker BL, Roberge JY, Bhanot P. Gilleran JA, et al. Among authors: de souza ml. J Med Chem. 2024 Jul 25;67(14):12459. doi: 10.1021/acs.jmedchem.4c01411. Epub 2024 Jul 10. J Med Chem. 2024. PMID: 38984428 No abstract available.
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
Xie SC, Wang Y, Morton CJ, Metcalfe RD, Dogovski C, Pasaje CFA, Dunn E, Luth MR, Kumpornsin K, Istvan ES, Park JS, Fairhurst KJ, Ketprasit N, Yeo T, Yildirim O, Bhebhe MN, Klug DM, Rutledge PJ, Godoy LC, Dey S, De Souza ML, Siqueira-Neto JL, Du Y, Puhalovich T, Amini M, Shami G, Loesbanluechai D, Nie S, Williamson N, Jana GP, Maity BC, Thomson P, Foley T, Tan DS, Niles JC, Han BW, Goldberg DE, Burrows J, Fidock DA, Lee MCS, Winzeler EA, Griffin MDW, Todd MH, Tilley L. Xie SC, et al. Among authors: de souza ml. Res Sq [Preprint]. 2023 Jul 27:rs.3.rs-3198291. doi: 10.21203/rs.3.rs-3198291/v1. Res Sq. 2023. Update in: Nat Commun. 2024 Jan 31;15(1):937. doi: 10.1038/s41467-024-45224-z PMID: 37546892 Free PMC article. Updated. Preprint.
Caspase-1 Variants and Plasma IL-1β in Patients with Leishmania guyanensis Cutaneous Leishmaniasis in the Amazonas.
de Souza JL, de Farias Guerra MV, de Mesquita TGR, Junior JDES, Sequera HDG, da Silva LS, da Silva LA, Moura FM, Menescal LSF, da Costa Torres J, Pinheiro SK, Kerr HKA, Ogusku MM, de Souza MLG, de Moura Neto JP, Sadahiro A, Ramasawmy R. de Souza JL, et al. Among authors: de souza mlg. Int J Mol Sci. 2024 Nov 19;25(22):12438. doi: 10.3390/ijms252212438. Int J Mol Sci. 2024. PMID: 39596502 Free PMC article.
151 results