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Page 1
A humanized mouse model of chronic COVID-19.
Sefik E, Israelow B, Mirza H, Zhao J, Qu R, Kaffe E, Song E, Halene S, Meffre E, Kluger Y, Nussenzweig M, Wilen CB, Iwasaki A, Flavell RA. Sefik E, et al. Among authors: wilen cb. Nat Biotechnol. 2022 Jun;40(6):906-920. doi: 10.1038/s41587-021-01155-4. Epub 2021 Dec 17. Nat Biotechnol. 2022. PMID: 34921308 Free PMC article.
Live Imaging of SARS-CoV-2 Infection in Mice Reveals Neutralizing Antibodies Require Fc Function for Optimal Efficacy.
Ullah I, Prévost J, Ladinsky MS, Stone H, Lu M, Anand SP, Beaudoin-Bussières G, Symmes K, Benlarbi M, Ding S, Gasser R, Fink C, Chen Y, Tauzin A, Goyette G, Bourassa C, Medjahed H, Mack M, Chung K, Wilen CB, Dekaban GA, Dikeakos JD, Bruce EA, Kaufmann DE, Stamatatos L, McGuire AT, Richard J, Pazgier M, Bjorkman PJ, Mothes W, Finzi A, Kumar P, Uchil PD. Ullah I, et al. Among authors: wilen cb. bioRxiv [Preprint]. 2021 Jun 28:2021.03.22.436337. doi: 10.1101/2021.03.22.436337. bioRxiv. 2021. Update in: Immunity. 2021 Sep 14;54(9):2143-2158.e15. doi: 10.1016/j.immuni.2021.08.015 PMID: 33791699 Free PMC article. Updated. Preprint.
Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium.
Ravindra NG, Alfajaro MM, Gasque V, Habet V, Wei J, Filler RB, Huston NC, Wan H, Szigeti-Buck K, Wang B, Wang G, Montgomery RR, Eisenbarth SC, Williams A, Pyle AM, Iwasaki A, Horvath TL, Foxman EF, Pierce RW, van Dijk D, Wilen CB. Ravindra NG, et al. Among authors: wilen cb. bioRxiv [Preprint]. 2020 Jul 13:2020.05.06.081695. doi: 10.1101/2020.05.06.081695. bioRxiv. 2020. Update in: PLoS Biol. 2021 Mar 17;19(3):e3001143. doi: 10.1371/journal.pbio.3001143 PMID: 32511382 Free PMC article. Updated. Preprint.
Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling.
Israelow B, Song E, Mao T, Lu P, Meir A, Liu F, Alfajaro MM, Wei J, Dong H, Homer RJ, Ring A, Wilen CB, Iwasaki A. Israelow B, et al. Among authors: wilen cb. bioRxiv [Preprint]. 2020 May 27:2020.05.27.118893. doi: 10.1101/2020.05.27.118893. bioRxiv. 2020. Update in: J Exp Med. 2020 Dec 7;217(12):e20201241. doi: 10.1084/jem.20201241 PMID: 32577647 Free PMC article. Updated. Preprint.
Neuroinvasion of SARS-CoV-2 in human and mouse brain.
Song E, Zhang C, Israelow B, Lu-Culligan A, Prado AV, Skriabine S, Lu P, Weizman OE, Liu F, Dai Y, Szigeti-Buck K, Yasumoto Y, Wang G, Castaldi C, Heltke J, Ng E, Wheeler J, Alfajaro MM, Levavasseur E, Fontes B, Ravindra NG, Van Dijk D, Mane S, Gunel M, Ring A, Kazmi SAJ, Zhang K, Wilen CB, Horvath TL, Plu I, Haik S, Thomas JL, Louvi A, Farhadian SF, Huttner A, Seilhean D, Renier N, Bilguvar K, Iwasaki A. Song E, et al. Among authors: wilen cb. bioRxiv [Preprint]. 2020 Sep 8:2020.06.25.169946. doi: 10.1101/2020.06.25.169946. bioRxiv. 2020. Update in: J Exp Med. 2021 Mar 1;218(3):e20202135. doi: 10.1084/jem.20202135 PMID: 32935108 Free PMC article. Updated. Preprint.
Neuroinvasion of SARS-CoV-2 in human and mouse brain.
Song E, Zhang C, Israelow B, Lu-Culligan A, Prado AV, Skriabine S, Lu P, Weizman OE, Liu F, Dai Y, Szigeti-Buck K, Yasumoto Y, Wang G, Castaldi C, Heltke J, Ng E, Wheeler J, Alfajaro MM, Levavasseur E, Fontes B, Ravindra NG, Van Dijk D, Mane S, Gunel M, Ring A, Kazmi SAJ, Zhang K, Wilen CB, Horvath TL, Plu I, Haik S, Thomas JL, Louvi A, Farhadian SF, Huttner A, Seilhean D, Renier N, Bilguvar K, Iwasaki A. Song E, et al. Among authors: wilen cb. J Exp Med. 2021 Mar 1;218(3):e20202135. doi: 10.1084/jem.20202135. J Exp Med. 2021. PMID: 33433624 Free PMC article.
Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes.
Ravindra NG, Alfajaro MM, Gasque V, Huston NC, Wan H, Szigeti-Buck K, Yasumoto Y, Greaney AM, Habet V, Chow RD, Chen JS, Wei J, Filler RB, Wang B, Wang G, Niklason LE, Montgomery RR, Eisenbarth SC, Chen S, Williams A, Iwasaki A, Horvath TL, Foxman EF, Pierce RW, Pyle AM, van Dijk D, Wilen CB. Ravindra NG, et al. Among authors: wilen cb. PLoS Biol. 2021 Mar 17;19(3):e3001143. doi: 10.1371/journal.pbio.3001143. eCollection 2021 Mar. PLoS Biol. 2021. PMID: 33730024 Free PMC article.
A stem-loop RNA RIG-I agonist protects against acute and chronic SARS-CoV-2 infection in mice.
Mao T, Israelow B, Lucas C, Vogels CBF, Gomez-Calvo ML, Fedorova O, Breban MI, Menasche BL, Dong H, Linehan M; Yale SARS-CoV-2 Genome Surveillance Initiative; Wilen CB, Landry ML, Grubaugh ND, Pyle AM, Iwasaki A. Mao T, et al. Among authors: wilen cb. J Exp Med. 2022 Jan 3;219(1):e20211818. doi: 10.1084/jem.20211818. Epub 2021 Nov 10. J Exp Med. 2022. PMID: 34757384 Free PMC article.
119 results