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Page 1
A Pan-Respiratory Antiviral Chemotype Targeting a Host Multi-Protein Complex.
Michon M, Müller-Schiffmann A, Lingappa AF, Yu SF, Du L, Deiter F, Broce S, Mallesh S, Crabtree J, Lingappa UF, Macieik A, Müller L, Ostermann PN, Andrée M, Adams O, Schaal H, Hogan RJ, Tripp RA, Appaiah U, Anand SK, Campi TW, Ford MJ, Reed JC, Lin J, Akintunde O, Copeland K, Nichols C, Petrouski E, Moreira AR, Jiang IT, DeYarman N, Brown I, Lau S, Segal I, Goldsmith D, Hong S, Asundi V, Briggs EM, Phyo NS, Froehlich M, Onisko B, Matlack K, Dey D, Lingappa JR, Prasad MD, Kitaygorodskyy A, Solas D, Boushey H, Greenland J, Pillai S, Lo MK, Montgomery JM, Spiropoulou CF, Korth C, Selvarajah S, Paulvannan K, Lingappa VR. Michon M, et al. Among authors: lingappa vr. bioRxiv [Preprint]. 2023 Dec 12:2021.01.17.426875. doi: 10.1101/2021.01.17.426875. bioRxiv. 2023. Update in: Open Biol. 2024 Jun;14(6):230363. doi: 10.1098/rsob.230363 PMID: 34931190 Free PMC article. Updated. Preprint.
A Novel Viral Assembly Inhibitor Blocks SARS-CoV-2 Replication in Airway Epithelial Cells.
Pillai S, Du L, Deiter F, Bouzidi M, Billaud JN, Graham S, Prerna D, Selvarajah S, Lingappa A, Michon M, Yu S, Paulvannan K, Lingappa V, Boushey H, Greenland J. Pillai S, et al. Res Sq [Preprint]. 2023 May 17:rs.3.rs-2887435. doi: 10.21203/rs.3.rs-2887435/v1. Res Sq. 2023. Update in: Commun Biol. 2024 Apr 22;7(1):486. doi: 10.1038/s42003-024-06130-8 PMID: 37292622 Free PMC article. Updated. Preprint.
A viral assembly inhibitor blocks SARS-CoV-2 replication in airway epithelial cells.
Du L, Deiter F, Bouzidi MS, Billaud JN, Simmons G, Dabral P, Selvarajah S, Lingappa AF, Michon M, Yu SF, Paulvannan K, Manicassamy B, Lingappa VR, Boushey H, Greenland JR, Pillai SK. Du L, et al. Among authors: lingappa vr. Commun Biol. 2024 Apr 22;7(1):486. doi: 10.1038/s42003-024-06130-8. Commun Biol. 2024. PMID: 38649430 Free PMC article.
A pan-respiratory antiviral chemotype targeting a transient host multi-protein complex.
Michon M, Müller-Schiffmann A, Lingappa AF, Yu SF, Du L, Deiter F, Broce S, Mallesh S, Crabtree J, Lingappa UF, Macieik A, Müller L, Ostermann PN, Andrée M, Adams O, Schaal H, Hogan RJ, Tripp RA, Appaiah U, Anand SK, Campi TW, Ford MJ, Reed JC, Lin J, Akintunde O, Copeland K, Nichols C, Petrouski E, Moreira AR, Jiang IT, DeYarman N, Brown I, Lau S, Segal I, Goldsmith D, Hong S, Asundi V, Briggs EM, Phyo NS, Froehlich M, Onisko B, Matlack K, Dey D, Lingappa JR, Prasad DM, Kitaygorodskyy A, Solas D, Boushey H, Greenland J, Pillai S, Lo MK, Montgomery JM, Spiropoulou CF, Korth C, Selvarajah S, Paulvannan K, Lingappa VR. Michon M, et al. Among authors: lingappa vr. Open Biol. 2024 Jun;14(6):230363. doi: 10.1098/rsob.230363. Epub 2024 Jun 19. Open Biol. 2024. PMID: 38889796 Free PMC article.
Small molecule protein assembly modulators with pan-cancer therapeutic efficacy.
Lingappa AF, Akintunde O, Samueli E, Ewald C, Michon M, Ziari N, Lu M, Yu SF, Froehlich M, Le PU, Fernandez Y, Mallesh S, Lin J, Kitaygorodskyy A, Solas D, Reed JC, Lingappa JR, Müller-Schiffmann A, Korth C, Prasad D, Nalca A, Aston E, Fabbri B, Anand SK, Campi TW, Petrouski E, Dey D, Andrews DW, Rubenstein JL, Lingappa VR. Lingappa AF, et al. Among authors: lingappa vr. Open Biol. 2024 Dec;14(12):240210. doi: 10.1098/rsob.240210. Epub 2024 Dec 18. Open Biol. 2024. PMID: 39689856 Free PMC article.
Multifunctionality of prostatic acid phosphatase in prostate cancer pathogenesis.
Alpert E, Akhavan A, Gruzman A, Hansen WJ, Lehrer-Graiwer J, Hall SC, Johansen E, McAllister S, Gulati M, Lin MF, Lingappa VR. Alpert E, et al. Among authors: lingappa vr. Biosci Rep. 2021 Oct 29;41(10):BSR20211646. doi: 10.1042/BSR20211646. Biosci Rep. 2021. PMID: 34677582 Free PMC article.
Multifunctionality of Prostatic Acid Phosphatase in Prostate  Cancer Pathogenesis.
Alpert E, Akhavan A, Gruzman A, Hansen WJ, Lehrer-Graiwer J, Hall SC, Johansen E, McAllister S, Gulati M, Lin MF, Lingappa VR. Alpert E, et al. Among authors: lingappa vr. Biosci Rep. 2021 Oct 4:BSR20211646. doi: 10.1042/BCJ20200944. Online ahead of print. Biosci Rep. 2021. PMID: 34605872 Free article.
New methylene blue derivatives suggest novel anti-orthopoxviral strategies.
Priyamvada L, Burgado J, Baker-Wagner M, Kitaygorodskyy A, Olson V, Lingappa VR, Satheshkumar PS. Priyamvada L, et al. Among authors: lingappa vr. Antiviral Res. 2021 Jul;191:105086. doi: 10.1016/j.antiviral.2021.105086. Epub 2021 May 13. Antiviral Res. 2021. PMID: 33992710 Free PMC article.
102 results