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A Pan-Respiratory Antiviral Chemotype Targeting a Host Multi-Protein Complex.
Michon M, Müller-Schiffmann A, Lingappa AF, Yu SF, Du L, Deiter F, Broce S, Mallesh S, Crabtree J, Lingappa UF, Macieik A, Müller L, Ostermann PN, Andrée M, Adams O, Schaal H, Hogan RJ, Tripp RA, Appaiah U, Anand SK, Campi TW, Ford MJ, Reed JC, Lin J, Akintunde O, Copeland K, Nichols C, Petrouski E, Moreira AR, Jiang IT, DeYarman N, Brown I, Lau S, Segal I, Goldsmith D, Hong S, Asundi V, Briggs EM, Phyo NS, Froehlich M, Onisko B, Matlack K, Dey D, Lingappa JR, Prasad MD, Kitaygorodskyy A, Solas D, Boushey H, Greenland J, Pillai S, Lo MK, Montgomery JM, Spiropoulou CF, Korth C, Selvarajah S, Paulvannan K, Lingappa VR. Michon M, et al. Among authors: nichols c. bioRxiv [Preprint]. 2023 Dec 12:2021.01.17.426875. doi: 10.1101/2021.01.17.426875. bioRxiv. 2023. Update in: Open Biol. 2024 Jun;14(6):230363. doi: 10.1098/rsob.230363 PMID: 34931190 Free PMC article. Updated. Preprint.
Host-rabies virus protein-protein interactions as druggable antiviral targets.
Lingappa UF, Wu X, Macieik A, Yu SF, Atuegbu A, Corpuz M, Francis J, Nichols C, Calayag A, Shi H, Ellison JA, Harrell EK, Asundi V, Lingappa JR, Prasad MD, Lipkin WI, Dey D, Hurt CR, Lingappa VR, Hansen WJ, Rupprecht CE. Lingappa UF, et al. Among authors: nichols c. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):E861-8. doi: 10.1073/pnas.1210198110. Epub 2013 Feb 12. Proc Natl Acad Sci U S A. 2013. PMID: 23404707 Free PMC article.
A pan-respiratory antiviral chemotype targeting a transient host multi-protein complex.
Michon M, Müller-Schiffmann A, Lingappa AF, Yu SF, Du L, Deiter F, Broce S, Mallesh S, Crabtree J, Lingappa UF, Macieik A, Müller L, Ostermann PN, Andrée M, Adams O, Schaal H, Hogan RJ, Tripp RA, Appaiah U, Anand SK, Campi TW, Ford MJ, Reed JC, Lin J, Akintunde O, Copeland K, Nichols C, Petrouski E, Moreira AR, Jiang IT, DeYarman N, Brown I, Lau S, Segal I, Goldsmith D, Hong S, Asundi V, Briggs EM, Phyo NS, Froehlich M, Onisko B, Matlack K, Dey D, Lingappa JR, Prasad DM, Kitaygorodskyy A, Solas D, Boushey H, Greenland J, Pillai S, Lo MK, Montgomery JM, Spiropoulou CF, Korth C, Selvarajah S, Paulvannan K, Lingappa VR. Michon M, et al. Among authors: nichols c. Open Biol. 2024 Jun;14(6):230363. doi: 10.1098/rsob.230363. Epub 2024 Jun 19. Open Biol. 2024. PMID: 38889796 Free PMC article.
Regional differences in three-dimensional fiber organization, smooth muscle cell phenotype, and contractility in the pregnant mouse cervix.
Hansen CJ, Rogers JH, Brown AJ, Boatwright N, Siricilla S, O'Brien CM, Panja S, Nichols CM, Devanathan K, Hardy BM, Does MD, Anderson AW, Paria BC, Mahadevan-Jansen A, Reese J, Herington JL. Hansen CJ, et al. Among authors: nichols cm. Sci Adv. 2024 Dec 20;10(51):eadr3530. doi: 10.1126/sciadv.adr3530. Epub 2024 Dec 18. Sci Adv. 2024. PMID: 39693423 Free PMC article.
A CRISPRi Library Screen in Group B Streptococcus Identifies Surface Immunogenic Protein (Sip) as a Mediator of Multiple Host Interactions.
Firestone K, Gopalakrishna KP, Rogers LM, Peters A, Gaddy JA, Nichols C, Hall MH, Varela HN, Carlin SM, Hillebrand GH, Giacobe EJ, Aronoff DM, Hooven TA. Firestone K, et al. Among authors: nichols c. bioRxiv [Preprint]. 2024 Dec 7:2024.12.06.627252. doi: 10.1101/2024.12.06.627252. bioRxiv. 2024. PMID: 39677656 Free PMC article. Preprint.
1,371 results