Lu H - Search Results

1

Engagement of the costimulatory molecule ICOS in tissues promotes establishment of CD8⁺ tissue-resident memory T cells.

Peng C, Huggins MA, Wanhainen KM, Knutson TP, Lu H, Georgiev H, Mittelsteadt KL, Jarjour NN, Wang H, Hogquist KA, Campbell DJ, Borges da Silva H, Jameson SC. Peng C, et al. Among authors: lu h. Immunity. 2022 Jan 11;55(1):98-114.e5. doi: 10.1016/j.immuni.2021.11.017. Epub 2021 Dec 20. Immunity. 2022. PMID: 34932944 Free PMC article.

2

A B-Cell-Specific Enhancer Orchestrates Nuclear Architecture to Generate a Diverse Antigen Receptor Repertoire.

Barajas-Mora EM, Kleiman E, Xu J, Carrico NC, Lu H, Oltz EM, Murre C, Feeney AJ. Barajas-Mora EM, et al. Among authors: lu h. Mol Cell. 2019 Jan 3;73(1):48-60.e5. doi: 10.1016/j.molcel.2018.10.013. Epub 2018 Nov 15. Mol Cell. 2019. PMID: 30449725 Free PMC article.

3

Calcium signaling instructs NIPBL recruitment at active enhancers and promoters via distinct mechanisms to reconstruct genome compartmentalization.

Zhu Y, Denholtz M, Lu H, Murre C. Zhu Y, et al. Among authors: lu h. Genes Dev. 2021 Jan 1;35(1-2):65-81. doi: 10.1101/gad.343475.120. Epub 2020 Dec 17. Genes Dev. 2021. PMID: 33334824 Free PMC article.

4

RNAs interact with BRD4 to promote enhanced chromatin engagement and transcription activation.

Rahnamoun H, Lee J, Sun Z, Lu H, Ramsey KM, Komives EA, Lauberth SM. Rahnamoun H, et al. Among authors: lu h. Nat Struct Mol Biol. 2018 Aug;25(8):687-697. doi: 10.1038/s41594-018-0102-0. Epub 2018 Aug 3. Nat Struct Mol Biol. 2018. PMID: 30076409 Free PMC article.

5

Upon microbial challenge, human neutrophils undergo rapid changes in nuclear architecture and chromatin folding to orchestrate an immediate inflammatory gene program.

Denholtz M, Zhu Y, He Z, Lu H, Isoda T, Döhrmann S, Nizet V, Murre C. Denholtz M, et al. Among authors: lu h. Genes Dev. 2020 Feb 1;34(3-4):149-165. doi: 10.1101/gad.333708.119. Epub 2020 Jan 9. Genes Dev. 2020. PMID: 31919189 Free PMC article.

6

Transcriptional network governing extraembryonic endoderm cell fate choice.

Pham PD, Lu H, Han H, Zhou JJ, Madan A, Wang W, Murre C, Cho KWY. Pham PD, et al. Among authors: lu h. Dev Biol. 2023 Oct;502:20-37. doi: 10.1016/j.ydbio.2023.07.002. Epub 2023 Jul 7. Dev Biol. 2023. PMID: 37423592 Free PMC article.

7

Mutant p53 regulates enhancer-associated H3K4 monomethylation through interactions with the methyltransferase MLL4.

Rahnamoun H, Hong J, Sun Z, Lee J, Lu H, Lauberth SM. Rahnamoun H, et al. Among authors: lu h. J Biol Chem. 2018 Aug 24;293(34):13234-13246. doi: 10.1074/jbc.RA118.003387. Epub 2018 Jun 28. J Biol Chem. 2018. PMID: 29954944 Free PMC article.

8

Mutant p53 shapes the enhancer landscape of cancer cells in response to chronic immune signaling.

Rahnamoun H, Lu H, Duttke SH, Benner C, Glass CK, Lauberth SM. Rahnamoun H, et al. Among authors: lu h. Nat Commun. 2017 Sep 29;8(1):754. doi: 10.1038/s41467-017-01117-y. Nat Commun. 2017. PMID: 28963538 Free PMC article.

9

Nuclear morphology is shaped by loop-extrusion programs.

Patta I, Zand M, Lee L, Mishra S, Bortnick A, Lu H, Prusty A, McArdle S, Mikulski Z, Wang HY, Cheng CS, Fisch KM, Hu M, Murre C. Patta I, et al. Among authors: lu h. Nature. 2024 Mar;627(8002):196-203. doi: 10.1038/s41586-024-07086-9. Epub 2024 Feb 14. Nature. 2024. PMID: 38355805 Free PMC article.

10

Enhancer-instructed epigenetic landscape and chromatin compartmentalization dictate a primary antibody repertoire protective against specific bacterial pathogens.

Barajas-Mora EM, Lee L, Lu H, Valderrama JA, Bjanes E, Nizet V, Feeney AJ, Hu M, Murre C. Barajas-Mora EM, et al. Among authors: lu h. Nat Immunol. 2023 Feb;24(2):320-336. doi: 10.1038/s41590-022-01402-z. Epub 2023 Jan 30. Nat Immunol. 2023. PMID: 36717722 Free PMC article.

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