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MAPK-mediated PHGDH induction is essential for melanoma formation and represents an actionable vulnerability.
Jasani N, Xu X, Posorske B, Kim Y, Vera O, Tsai KY, DeNicola GM, Karreth FA. Jasani N, et al. Among authors: karreth fa. bioRxiv [Preprint]. 2024 Apr 15:2024.04.11.589139. doi: 10.1101/2024.04.11.589139. bioRxiv. 2024. Update in: Cancer Res. 2025 Jan 15;85(2):314-328. doi: 10.1158/0008-5472.CAN-24-2471 PMID: 38659816 Free PMC article. Updated. Preprint.
Linc-ing Circulating Long Non-coding RNAs to the Diagnosis and Malignant Prediction of Intraductal Papillary Mucinous Neoplasms of the Pancreas.
Permuth JB, Chen DT, Yoder SJ, Li J, Smith AT, Choi JW, Kim J, Balagurunathan Y, Jiang K, Coppola D, Centeno BA, Klapman J, Hodul P, Karreth FA, Trevino JG, Merchant N, Magliocco A, Malafa MP, Gillies R. Permuth JB, et al. Among authors: karreth fa. Sci Rep. 2017 Sep 5;7(1):10484. doi: 10.1038/s41598-017-09754-5. Sci Rep. 2017. PMID: 28874676 Free PMC article.
A Versatile ES Cell-Based Melanoma Mouse Modeling Platform.
Bok I, Vera O, Xu X, Jasani N, Nakamura K, Reff J, Nenci A, Gonzalez JG, Karreth FA. Bok I, et al. Among authors: karreth fa. Cancer Res. 2020 Feb 15;80(4):912-921. doi: 10.1158/0008-5472.CAN-19-2924. Epub 2019 Nov 19. Cancer Res. 2020. PMID: 31744817 Free PMC article.
A Mutational Survey of Acral Nevi.
Smalley KSM, Teer JK, Chen YA, Wu JY, Yao J, Koomen JM, Chen WS, Rodriguez-Waitkus P, Karreth FA, Messina JL. Smalley KSM, et al. Among authors: karreth fa. JAMA Dermatol. 2021 Jul 1;157(7):831-835. doi: 10.1001/jamadermatol.2021.0793. JAMA Dermatol. 2021. PMID: 33978681 Free PMC article.
Single-cell Characterization of the Cellular Landscape of Acral Melanoma Identifies Novel Targets for Immunotherapy.
Li J, Smalley I, Chen Z, Wu JY, Phadke MS, Teer JK, Nguyen T, Karreth FA, Koomen JM, Sarnaik AA, Zager JS, Khushalani NI, Tarhini AA, Sondak VK, Rodriguez PC, Messina JL, Chen YA, Smalley KSM. Li J, et al. Among authors: karreth fa. Clin Cancer Res. 2022 May 13;28(10):2131-2146. doi: 10.1158/1078-0432.CCR-21-3145. Clin Cancer Res. 2022. PMID: 35247927 Free PMC article.
A MAPK/miR-29 Axis Suppresses Melanoma by Targeting MAFG and MYBL2.
Vera O, Bok I, Jasani N, Nakamura K, Xu X, Mecozzi N, Angarita A, Wang K, Tsai KY, Karreth FA. Vera O, et al. Among authors: karreth fa. Cancers (Basel). 2021 Mar 19;13(6):1408. doi: 10.3390/cancers13061408. Cancers (Basel). 2021. PMID: 33808771 Free PMC article.
58 results