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Differential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell Microenvironments.
Kester L, Seinstra D, van Rossum AGJ, Vennin C, Hoogstraat M, van der Velden D, Opdam M, van Werkhoven E, Hahn K, Nederlof I, Lips EH, Mandjes IAM, van Leeuwen-Stok AE, Canisius S, van Tinteren H, Imholz ALT, Portielje JEA, Bos MEMM, Bakker SD, Rutgers EJ, Horlings HM, Wesseling J, Voest EE, Wessels LFA, Kok M, Oosterkamp HM, van Oudenaarden A, Linn SC, van Rheenen J. Kester L, et al. Among authors: horlings hm. Clin Cancer Res. 2022 Mar 1;28(5):960-971. doi: 10.1158/1078-0432.CCR-21-1442. Clin Cancer Res. 2022. PMID: 34965952 Free PMC article.
PatchSorter: a high throughput deep learning digital pathology tool for object labeling.
Walker C, Talawalla T, Toth R, Ambekar A, Rea K, Chamian O, Fan F, Berezowska S, Rottenberg S, Madabhushi A, Maillard M, Barisoni L, Horlings HM, Janowczyk A. Walker C, et al. Among authors: horlings hm. NPJ Digit Med. 2024 Jun 20;7(1):164. doi: 10.1038/s41746-024-01150-4. NPJ Digit Med. 2024. PMID: 38902336 Free PMC article.
The Information Technology (IT) Infrastructure of the Multicenter Archipelago of Ovarian Cancer Research Biobank: A Potential Blueprint for Other Biobanks.
Zelisse HS, de Ridder S, van Gent MDJM, Mom CH, Wisman GBA, Roes EM, Reyners AKL, Piek JM, Nieuwenhuyzen-de Boer GM, Lok CAR, de Kroon CD, Kooreman LFS, Janssen MJ, Jansen MPHM, Horlings HM, Collée M, Broeks A, Boere IA, Bart J, van Altena AM, Heeling M, Stoter IM, Voorham QJ, van de Vijver MJ, Dijk F, Belien JAM; Archipelago of Ovarian Cancer Research Consortium. Zelisse HS, et al. Among authors: horlings hm. Biopreserv Biobank. 2024 Dec;22(6):568-577. doi: 10.1089/bio.2023.0118. Epub 2024 Apr 29. Biopreserv Biobank. 2024. PMID: 38682281
A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer.
Berns K, Horlings HM, Hennessy BT, Madiredjo M, Hijmans EM, Beelen K, Linn SC, Gonzalez-Angulo AM, Stemke-Hale K, Hauptmann M, Beijersbergen RL, Mills GB, van de Vijver MJ, Bernards R. Berns K, et al. Among authors: horlings hm. Cancer Cell. 2007 Oct;12(4):395-402. doi: 10.1016/j.ccr.2007.08.030. Cancer Cell. 2007. PMID: 17936563 Free article. Clinical Trial.
A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the proliferation, immune response and RNA splicing modules in breast cancer.
Reyal F, van Vliet MH, Armstrong NJ, Horlings HM, de Visser KE, Kok M, Teschendorff AE, Mook S, van 't Veer L, Caldas C, Salmon RJ, van de Vijver MJ, Wessels LF. Reyal F, et al. Among authors: horlings hm. Breast Cancer Res. 2008;10(6):R93. doi: 10.1186/bcr2192. Epub 2008 Nov 13. Breast Cancer Res. 2008. PMID: 19014521 Free PMC article.
138 results