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Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
Wei P, Song G, Shi M, Zhou Y, Liu Y, Lei J, Chen P, Yin L. Wei P, et al. FASEB J. 2018 Feb;32(2):1085-1098. doi: 10.1096/fj.201700705R. Epub 2018 Jan 3. FASEB J. 2018. PMID: 29079699
These data demonstrate the crucial role of the PEA- and lipid A-binding pockets and provide novel insights into the structure-based mechanisms, important drug-target hot spots, and a drug template for further drug development to combat the urgent, rising threat of MCR-1-mediated …
These data demonstrate the crucial role of the PEA- and lipid A-binding pockets and provide novel insights into the structure-based mechanis …
The Lambda variant of SARS-CoV-2 has a better chance than the Delta variant to escape vaccines.
Liu H, Wei P, Zhang Q, Aviszus K, Linderberger J, Yang J, Liu J, Chen Z, Waheed H, Reynoso L, Downey GP, Frankel SK, Kappler J, Marrack P, Zhang G. Liu H, et al. Among authors: wei p. bioRxiv [Preprint]. 2021 Aug 26:2021.08.25.457692. doi: 10.1101/2021.08.25.457692. bioRxiv. 2021. Update in: Int J Mol Sci. 2022 Sep 26;23(19):11325. doi: 10.3390/ijms231911325 PMID: 34462744 Free PMC article. Updated. Preprint.
3,832 results