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Engineered High-Affinity ACE2 Peptide Mitigates ARDS and Death Induced by Multiple SARS-CoV-2 Variants.
Zhang L, Dutta S, Xiong S, Chan M, Chan KK, Fan TM, Bailey KL, Lindeblad M, Cooper LM, Rong L, Gugliuzza AF, Shukla D, Procko E, Rehman J, Malik AB. Zhang L, et al. Among authors: rong l. bioRxiv [Preprint]. 2021 Dec 22:2021.12.21.473668. doi: 10.1101/2021.12.21.473668. bioRxiv. 2021. Update in: Nat Chem Biol. 2022 Mar;18(3):342-351. doi: 10.1038/s41589-021-00965-6 PMID: 34981059 Free PMC article. Updated. Preprint.
An engineered ACE2 decoy receptor can be administered by inhalation and potently targets the BA.1 and BA.2 omicron variants of SARS-CoV-2.
Zhang L, Narayanan KK, Cooper L, Chan KK, Devlin CA, Aguhob A, Shirley K, Rong L, Rehman J, Malik AB, Procko E. Zhang L, et al. Among authors: rong l. bioRxiv [Preprint]. 2022 Mar 28:2022.03.28.486075. doi: 10.1101/2022.03.28.486075. bioRxiv. 2022. Update in: EMBO Mol Med. 2022 Nov 8;14(11):e16109. doi: 10.15252/emmm.202216109 PMID: 35378764 Free PMC article. Updated. Preprint.
Non-Covalent Inhibitors of SARS-CoV-2 Papain-Like Protease (PLpro): In Vitro and In Vivo Antiviral Activity.
Velma GR, Shen Z, Holberg C, Fu J, Soleymani F, Cooper L, Ramos OL, Indukuri D, Musku SR, Rychetsky P, Slilaty S, Li Z, Ratia K, Rong L, Schenten D, Xiong R, J Thatcher GR. Velma GR, et al. Among authors: rong l. J Med Chem. 2024 Aug 22;67(16):13681-13702. doi: 10.1021/acs.jmedchem.4c00378. Epub 2024 Aug 5. J Med Chem. 2024. PMID: 39102360 Free PMC article.
Development of SARS-CoV-2 entry antivirals.
Dong M, Galvan Achi JM, Du R, Rong L, Cui Q. Dong M, et al. Among authors: rong l. Cell Insight. 2024 Jan 30;3(1):100144. doi: 10.1016/j.cellin.2023.100144. eCollection 2024 Feb. Cell Insight. 2024. PMID: 38323318 Free PMC article. Review.
VLP-based model for the study of airborne viral pathogens.
Caffrey M, Jayakumar N, Caffrey V, Anirudhan V, Rong L, Paprotny I. Caffrey M, et al. Among authors: rong l. Microbiol Spectr. 2024 Jun 4;12(6):e0001324. doi: 10.1128/spectrum.00013-24. Epub 2024 May 16. Microbiol Spectr. 2024. PMID: 38752752 Free PMC article.
1,338 results