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Page 1
Non-neutralizing antibodies targeting the immunogenic regions of HIV-1 envelope reduce mucosal infection and virus burden in humanized mice.
Hioe CE, Li G, Liu X, Tsahouridis O, He X, Funaki M, Klingler J, Tang AF, Feyznezhad R, Heindel DW, Wang XH, Spencer DA, Hu G, Satija N, Prévost J, Finzi A, Hessell AJ, Wang S, Lu S, Chen BK, Zolla-Pazner S, Upadhyay C, Alvarez R, Su L. Hioe CE, et al. Among authors: finzi a. PLoS Pathog. 2022 Jan 5;18(1):e1010183. doi: 10.1371/journal.ppat.1010183. eCollection 2022 Jan. PLoS Pathog. 2022. PMID: 34986207 Free PMC article.
Interaction with cellular CD4 exposes HIV-1 envelope epitopes targeted by antibody-dependent cell-mediated cytotoxicity.
Veillette M, Désormeaux A, Medjahed H, Gharsallah NE, Coutu M, Baalwa J, Guan Y, Lewis G, Ferrari G, Hahn BH, Haynes BF, Robinson JE, Kaufmann DE, Bonsignori M, Sodroski J, Finzi A. Veillette M, et al. Among authors: finzi a. J Virol. 2014 Mar;88(5):2633-44. doi: 10.1128/JVI.03230-13. Epub 2013 Dec 18. J Virol. 2014. PMID: 24352444 Free PMC article.
Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses.
Moody MA, Gao F, Gurley TC, Amos JD, Kumar A, Hora B, Marshall DJ, Whitesides JF, Xia SM, Parks R, Lloyd KE, Hwang KK, Lu X, Bonsignori M, Finzi A, Vandergrift NA, Alam SM, Ferrari G, Shen X, Tomaras GD, Kamanga G, Cohen MS, Sam NE, Kapiga S, Gray ES, Tumba NL, Morris L, Zolla-Pazner S, Gorny MK, Mascola JR, Hahn BH, Shaw GM, Sodroski JG, Liao HX, Montefiori DC, Hraber PT, Korber BT, Haynes BF. Moody MA, et al. Among authors: finzi a. Cell Host Microbe. 2015 Sep 9;18(3):354-62. doi: 10.1016/j.chom.2015.08.006. Cell Host Microbe. 2015. PMID: 26355218 Free PMC article.
A Highly Conserved Residue of the HIV-1 gp120 Inner Domain Is Important for Antibody-Dependent Cellular Cytotoxicity Responses Mediated by Anti-cluster A Antibodies.
Ding S, Veillette M, Coutu M, Prévost J, Scharf L, Bjorkman PJ, Ferrari G, Robinson JE, Stürzel C, Hahn BH, Sauter D, Kirchhoff F, Lewis GK, Pazgier M, Finzi A. Ding S, et al. Among authors: finzi a. J Virol. 2015 Dec 4;90(4):2127-34. doi: 10.1128/JVI.02779-15. Print 2016 Feb 15. J Virol. 2015. PMID: 26637462 Free PMC article.
A Highly Conserved gp120 Inner Domain Residue Modulates Env Conformation and Trimer Stability.
Ding S, Tolbert WD, Prévost J, Pacheco B, Coutu M, Debbeche O, Xiang SH, Pazgier M, Finzi A. Ding S, et al. Among authors: finzi a. J Virol. 2016 Sep 12;90(19):8395-409. doi: 10.1128/JVI.01068-16. Print 2016 Oct 1. J Virol. 2016. PMID: 27384653 Free PMC article.
Previous studies have shown that highly conserved residues in the inner domain of gp120 are required for HIV-1 envelope glycoprotein (Env) transitions to the CD4-bound conformation (A. Finzi, S. H. Xiang, B. Pacheco, L. Wang, J. Haight, et al., Mol Cell 37:656-667, …
Previous studies have shown that highly conserved residues in the inner domain of gp120 are required for HIV-1 envelope glycoprotein (Env) t …
Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins.
Richard J, Pacheco B, Gohain N, Veillette M, Ding S, Alsahafi N, Tolbert WD, Prévost J, Chapleau JP, Coutu M, Jia M, Brassard N, Park J, Courter JR, Melillo B, Martin L, Tremblay C, Hahn BH, Kaufmann DE, Wu X, Smith AB 3rd, Sodroski J, Pazgier M, Finzi A. Richard J, et al. Among authors: finzi a. EBioMedicine. 2016 Oct;12:208-218. doi: 10.1016/j.ebiom.2016.09.004. Epub 2016 Sep 9. EBioMedicine. 2016. PMID: 27633463 Free PMC article.
517 results