Hernandez Y - Search Results

1

A naturally inspired antibiotic to target multidrug-resistant pathogens.

Wang Z, Koirala B, Hernandez Y, Zimmerman M, Park S, Perlin DS, Brady SF. Wang Z, et al. Among authors: hernandez y. Nature. 2022 Jan;601(7894):606-611. doi: 10.1038/s41586-021-04264-x. Epub 2022 Jan 5. Nature. 2022. PMID: 34987225 Free PMC article.

2

Identification of structurally diverse menaquinone-binding antibiotics with in vivo activity against multidrug-resistant pathogens.

Li L, Koirala B, Hernandez Y, MacIntyre LW, Ternei MA, Russo R, Brady SF. Li L, et al. Among authors: hernandez y. Nat Microbiol. 2022 Jan;7(1):120-131. doi: 10.1038/s41564-021-01013-8. Epub 2021 Dec 23. Nat Microbiol. 2022. PMID: 34949828 Free PMC article.

3

Lapcin, a potent dual topoisomerase I/II inhibitor discovered by soil metagenome guided total chemical synthesis.

Wang Z, Forelli N, Hernandez Y, Ternei M, Brady SF. Wang Z, et al. Among authors: hernandez y. Nat Commun. 2022 Feb 11;13(1):842. doi: 10.1038/s41467-022-28292-x. Nat Commun. 2022. PMID: 35149673 Free PMC article.

4

Bioinformatic prospecting and synthesis of a bifunctional lipopeptide antibiotic that evades resistance.

Wang Z, Koirala B, Hernandez Y, Zimmerman M, Brady SF. Wang Z, et al. Among authors: hernandez y. Science. 2022 May 27;376(6596):991-996. doi: 10.1126/science.abn4213. Epub 2022 May 26. Science. 2022. PMID: 35617397 Free PMC article.

5

Discovery of Paenibacillaceae Family Gram-Negative-Active Cationic Lipopeptide Antibiotics Using Evolution-Guided Chemical Synthesis.

Wang Z, Koirala B, Hernandez Y, Brady SF. Wang Z, et al. Among authors: hernandez y. Org Lett. 2022 Jul 15;24(27):4943-4948. doi: 10.1021/acs.orglett.2c01879. Epub 2022 Jul 1. Org Lett. 2022. PMID: 35776528 Free PMC article.

6

Biosynthetic Interrogation of Soil Metagenomes Reveals Metamarin, an Uncommon Cyclomarin Congener with Activity against Mycobacterium tuberculosis.

Li L, MacIntyre LW, Ali T, Russo R, Koirala B, Hernandez Y, Brady SF. Li L, et al. Among authors: hernandez y. J Nat Prod. 2021 Apr 23;84(4):1056-1066. doi: 10.1021/acs.jnatprod.0c01104. Epub 2021 Feb 23. J Nat Prod. 2021. PMID: 33621083 Free PMC article.

7

Fast, adaptive evolution at a bacterial host-resistance locus: the PFam54 gene array in Borrelia burgdorferi.

Wywial E, Haven J, Casjens SR, Hernandez YA, Singh S, Mongodin EF, Fraser-Liggett CM, Luft BJ, Schutzer SE, Qiu WG. Wywial E, et al. Gene. 2009 Sep 15;445(1-2):26-37. doi: 10.1016/j.gene.2009.05.017. Epub 2009 Jun 6. Gene. 2009. PMID: 19505540 Free PMC article.

8

Inter- and intra-specific pan-genomes of Borrelia burgdorferi sensu lato: genome stability and adaptive radiation.

Mongodin EF, Casjens SR, Bruno JF, Xu Y, Drabek EF, Riley DR, Cantarel BL, Pagan PE, Hernandez YA, Vargas LC, Dunn JJ, Schutzer SE, Fraser CM, Qiu WG, Luft BJ. Mongodin EF, et al. Among authors: hernandez ya. BMC Genomics. 2013 Oct 10;14:693. doi: 10.1186/1471-2164-14-693. BMC Genomics. 2013. PMID: 24112474 Free PMC article.

9

BpWrapper: BioPerl-based sequence and tree utilities for rapid prototyping of bioinformatics pipelines.

Hernández Y, Bernstein R, Pagan P, Vargas L, McCaig W, Ramrattan G, Akther S, Larracuente A, Di L, Vieira FG, Qiu WG. Hernández Y, et al. BMC Bioinformatics. 2018 Mar 2;19(1):76. doi: 10.1186/s12859-018-2074-9. BMC Bioinformatics. 2018. PMID: 29499649 Free PMC article.

10

Pervasive recombination and sympatric genome diversification driven by frequency-dependent selection in Borrelia burgdorferi, the Lyme disease bacterium.

Haven J, Vargas LC, Mongodin EF, Xue V, Hernandez Y, Pagan P, Fraser-Liggett CM, Schutzer SE, Luft BJ, Casjens SR, Qiu WG. Haven J, et al. Among authors: hernandez y. Genetics. 2011 Nov;189(3):951-66. doi: 10.1534/genetics.111.130773. Epub 2011 Sep 2. Genetics. 2011. PMID: 21890743 Free PMC article.

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