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Page 1
Increased energy demand from anabolic-catabolic processes drives β-lactam antibiotic lethality.
Lobritz MA, Andrews IW, Braff D, Porter CBM, Gutierrez A, Furuta Y, Cortes LBG, Ferrante T, Bening SC, Wong F, Gruber C, Bakerlee CW, Lambert G, Walker GC, Dwyer DJ, Collins JJ. Lobritz MA, et al. Among authors: andrews iw. Cell Chem Biol. 2022 Feb 17;29(2):276-286.e4. doi: 10.1016/j.chembiol.2021.12.010. Epub 2022 Jan 5. Cell Chem Biol. 2022. PMID: 34990601 Free PMC article.
Targeting Antibiotic Tolerance, Pathogen by Pathogen.
Meylan S, Andrews IW, Collins JJ. Meylan S, et al. Among authors: andrews iw. Cell. 2018 Mar 8;172(6):1228-1238. doi: 10.1016/j.cell.2018.01.037. Cell. 2018. PMID: 29522744 Free article. Review.
A Deep Learning Approach to Antibiotic Discovery.
Stokes JM, Yang K, Swanson K, Jin W, Cubillos-Ruiz A, Donghia NM, MacNair CR, French S, Carfrae LA, Bloom-Ackermann Z, Tran VM, Chiappino-Pepe A, Badran AH, Andrews IW, Chory EJ, Church GM, Brown ED, Jaakkola TS, Barzilay R, Collins JJ. Stokes JM, et al. Among authors: andrews iw. Cell. 2020 Feb 20;180(4):688-702.e13. doi: 10.1016/j.cell.2020.01.021. Cell. 2020. PMID: 32084340 Free PMC article.
Discovery of antibiotics that selectively kill metabolically dormant bacteria.
Zheng EJ, Valeri JA, Andrews IW, Krishnan A, Bandyopadhyay P, Anahtar MN, Herneisen A, Schulte F, Linnehan B, Wong F, Stokes JM, Renner LD, Lourido S, Collins JJ. Zheng EJ, et al. Among authors: andrews iw. Cell Chem Biol. 2024 Apr 18;31(4):712-728.e9. doi: 10.1016/j.chembiol.2023.10.026. Epub 2023 Nov 28. Cell Chem Biol. 2024. PMID: 38029756
A Deep Learning Approach to Antibiotic Discovery.
Stokes JM, Yang K, Swanson K, Jin W, Cubillos-Ruiz A, Donghia NM, MacNair CR, French S, Carfrae LA, Bloom-Ackermann Z, Tran VM, Chiappino-Pepe A, Badran AH, Andrews IW, Chory EJ, Church GM, Brown ED, Jaakkola TS, Barzilay R, Collins JJ. Stokes JM, et al. Among authors: andrews iw. Cell. 2020 Apr 16;181(2):475-483. doi: 10.1016/j.cell.2020.04.001. Cell. 2020. PMID: 32302574 Free article. No abstract available.
Dual responsive, stabilized nanoparticles for efficient in vivo plasmid delivery.
Wei H, Volpatti LR, Sellers DL, Maris DO, Andrews IW, Hemphill AS, Chan LW, Chu DS, Horner PJ, Pun SH. Wei H, et al. Among authors: andrews iw. Angew Chem Int Ed Engl. 2013 May 10;52(20):5377-81. doi: 10.1002/anie.201301896. Epub 2013 Apr 16. Angew Chem Int Ed Engl. 2013. PMID: 23592572 Free PMC article. No abstract available.