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Page 1
Genotype-specific features reduce the susceptibility of South American yellow fever virus strains to vaccine-induced antibodies.
Haslwanter D, Lasso G, Wec AZ, Furtado ND, Raphael LMS, Tse AL, Sun Y, Stransky S, Pedreño-Lopez N, Correia CA, Bornholdt ZA, Sakharkar M, Avelino-Silva VI, Moyer CL, Watkins DI, Kallas EG, Sidoli S, Walker LM, Bonaldo MC, Chandran K. Haslwanter D, et al. Among authors: bornholdt za. Cell Host Microbe. 2022 Feb 9;30(2):248-259.e6. doi: 10.1016/j.chom.2021.12.009. Epub 2022 Jan 7. Cell Host Microbe. 2022. PMID: 34998466 Free PMC article.
Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak.
Bornholdt ZA, Turner HL, Murin CD, Li W, Sok D, Souders CA, Piper AE, Goff A, Shamblin JD, Wollen SE, Sprague TR, Fusco ML, Pommert KB, Cavacini LA, Smith HL, Klempner M, Reimann KA, Krauland E, Gerngross TU, Wittrup KD, Saphire EO, Burton DR, Glass PJ, Ward AB, Walker LM. Bornholdt ZA, et al. Science. 2016 Mar 4;351(6277):1078-83. doi: 10.1126/science.aad5788. Epub 2016 Feb 18. Science. 2016. PMID: 26912366 Free PMC article.
A "Trojan horse" bispecific-antibody strategy for broad protection against ebolaviruses.
Wec AZ, Nyakatura EK, Herbert AS, Howell KA, Holtsberg FW, Bakken RR, Mittler E, Christin JR, Shulenin S, Jangra RK, Bharrhan S, Kuehne AI, Bornholdt ZA, Flyak AI, Saphire EO, Crowe JE Jr, Aman MJ, Dye JM, Lai JR, Chandran K. Wec AZ, et al. Among authors: bornholdt za. Science. 2016 Oct 21;354(6310):350-354. doi: 10.1126/science.aag3267. Epub 2016 Sep 8. Science. 2016. PMID: 27608667 Free PMC article.
Antibodies from a Human Survivor Define Sites of Vulnerability for Broad Protection against Ebolaviruses.
Wec AZ, Herbert AS, Murin CD, Nyakatura EK, Abelson DM, Fels JM, He S, James RM, de La Vega MA, Zhu W, Bakken RR, Goodwin E, Turner HL, Jangra RK, Zeitlin L, Qiu X, Lai JR, Walker LM, Ward AB, Dye JM, Chandran K, Bornholdt ZA. Wec AZ, et al. Among authors: bornholdt za. Cell. 2017 May 18;169(5):878-890.e15. doi: 10.1016/j.cell.2017.04.037. Cell. 2017. PMID: 28525755 Free PMC article.
Development of a Human Antibody Cocktail that Deploys Multiple Functions to Confer Pan-Ebolavirus Protection.
Wec AZ, Bornholdt ZA, He S, Herbert AS, Goodwin E, Wirchnianski AS, Gunn BM, Zhang Z, Zhu W, Liu G, Abelson DM, Moyer CL, Jangra RK, James RM, Bakken RR, Bohorova N, Bohorov O, Kim DH, Pauly MH, Velasco J, Bortz RH 3rd, Whaley KJ, Goldstein T, Anthony SJ, Alter G, Walker LM, Dye JM, Zeitlin L, Qiu X, Chandran K. Wec AZ, et al. Among authors: bornholdt za. Cell Host Microbe. 2019 Jan 9;25(1):39-48.e5. doi: 10.1016/j.chom.2018.12.004. Cell Host Microbe. 2019. PMID: 30629917 Free PMC article.
A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates.
Bornholdt ZA, Herbert AS, Mire CE, He S, Cross RW, Wec AZ, Abelson DM, Geisbert JB, James RM, Rahim MN, Zhu W, Borisevich V, Banadyga L, Gunn BM, Agans KN, Wirchnianski AS, Goodwin E, Tierney K, Shestowsky WS, Bohorov O, Bohorova N, Velasco J, Ailor E, Kim D, Pauly MH, Whaley KJ, Alter G, Walker LM, Chandran K, Zeitlin L, Qiu X, Geisbert TW, Dye JM. Bornholdt ZA, et al. Cell Host Microbe. 2019 Jan 9;25(1):49-58.e5. doi: 10.1016/j.chom.2018.12.005. Cell Host Microbe. 2019. PMID: 30629918 Free PMC article.
Structure and Characterization of Crimean-Congo Hemorrhagic Fever Virus GP38.
Mishra AK, Moyer CL, Abelson DM, Deer DJ, El Omari K, Duman R, Lobel L, Lutwama JJ, Dye JM, Wagner A, Chandran K, Cross RW, Geisbert TW, Zeitlin L, Bornholdt ZA, McLellan JS. Mishra AK, et al. Among authors: bornholdt za. J Virol. 2020 Mar 31;94(8):e02005-19. doi: 10.1128/JVI.02005-19. Print 2020 Mar 31. J Virol. 2020. PMID: 31996434 Free PMC article.
Development of an antibody cocktail for treatment of Sudan virus infection.
Herbert AS, Froude JW, Ortiz RA, Kuehne AI, Dorosky DE, Bakken RR, Zak SE, Josleyn NM, Musiychuk K, Jones RM, Green B, Streatfield SJ, Wec AZ, Bohorova N, Bohorov O, Kim DH, Pauly MH, Velasco J, Whaley KJ, Stonier SW, Bornholdt ZA, Chandran K, Zeitlin L, Sampey D, Yusibov V, Dye JM. Herbert AS, et al. Among authors: bornholdt za. Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3768-3778. doi: 10.1073/pnas.1914985117. Epub 2020 Feb 3. Proc Natl Acad Sci U S A. 2020. PMID: 32015126 Free PMC article.
44 results