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Serologic markers of Epstein-Barr virus reactivation are associated with increased disease activity, inflammation, and interferon pathway activation in patients with systemic lupus erythematosus.
Wood RA, Guthridge L, Thurmond E, Guthridge CJ, Kheir JM, Bourn RL, Wagner CA, Chen H, DeJager W, Macwana SR, Kamp S, Lu R, Arriens C, Chakravarty EF, Thanou A, Merrill JT, Guthridge JM, James JA. Wood RA, et al. Among authors: lu r. J Transl Autoimmun. 2021 Aug 31;4:100117. doi: 10.1016/j.jtauto.2021.100117. eCollection 2021. J Transl Autoimmun. 2021. PMID: 35005588 Free PMC article.
Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification.
Munroe ME, Lu R, Zhao YD, Fife DA, Robertson JM, Guthridge JM, Niewold TB, Tsokos GC, Keith MP, Harley JB, James JA. Munroe ME, et al. Among authors: lu r. Ann Rheum Dis. 2016 Nov;75(11):2014-2021. doi: 10.1136/annrheumdis-2015-208140. Epub 2016 Jan 25. Ann Rheum Dis. 2016. PMID: 27088255 Free PMC article.
Adults with systemic lupus exhibit distinct molecular phenotypes in a cross-sectional study.
Guthridge JM, Lu R, Tran LT, Arriens C, Aberle T, Kamp S, Munroe ME, Dominguez N, Gross T, DeJager W, Macwana SR, Bourn RL, Apel S, Thanou A, Chen H, Chakravarty EF, Merrill JT, James JA. Guthridge JM, et al. Among authors: lu r. EClinicalMedicine. 2020 Mar 4;20:100291. doi: 10.1016/j.eclinm.2020.100291. eCollection 2020 Mar. EClinicalMedicine. 2020. PMID: 32154507 Free PMC article.
Autoantibody-positive healthy individuals with lower lupus risk display a unique immune endotype.
Slight-Webb S, Smith M, Bylinska A, Macwana S, Guthridge C, Lu R, Merrill JT, Chakravarty E, Arriens C, Munroe ME, Maecker HT, Utz PJ, Guthridge JM, James JA. Slight-Webb S, et al. Among authors: lu r. J Allergy Clin Immunol. 2020 Dec;146(6):1419-1433. doi: 10.1016/j.jaci.2020.04.047. Epub 2020 May 22. J Allergy Clin Immunol. 2020. PMID: 32446964 Free PMC article. Clinical Trial.
Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK.
Castillejo-López C, Delgado-Vega AM, Wojcik J, Kozyrev SV, Thavathiru E, Wu YY, Sánchez E, Pöllmann D, López-Egido JR, Fineschi S, Domínguez N, Lu R, James JA, Merrill JT, Kelly JA, Kaufman KM, Moser KL, Gilkeson G, Frostegård J, Pons-Estel BA, D'Alfonso S, Witte T, Callejas JL, Harley JB, Gaffney PM, Martin J, Guthridge JM, Alarcón-Riquelme ME. Castillejo-López C, et al. Among authors: lu r. Ann Rheum Dis. 2012 Jan;71(1):136-42. doi: 10.1136/annrheumdis-2011-200085. Epub 2011 Oct 6. Ann Rheum Dis. 2012. PMID: 21978998 Free PMC article.
Comparison of autoantibody specificities between traditional and bead-based assays in a large, diverse collection of patients with systemic lupus erythematosus and family members.
Bruner BF, Guthridge JM, Lu R, Vidal G, Kelly JA, Robertson JM, Kamen DL, Gilkeson GS, Neas BR, Reichlin M, Scofield RH, Harley JB, James JA. Bruner BF, et al. Among authors: lu r. Arthritis Rheum. 2012 Nov;64(11):3677-86. doi: 10.1002/art.34651. Arthritis Rheum. 2012. PMID: 23112091 Free PMC article.
5,333 results