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Page 1
Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment.
Danis C, Dupré E, Zejneli O, Caillierez R, Arrial A, Bégard S, Mortelecque J, Eddarkaoui S, Loyens A, Cantrelle FX, Hanoulle X, Rain JC, Colin M, Buée L, Landrieu I. Danis C, et al. Among authors: loyens a. Mol Ther. 2022 Apr 6;30(4):1484-1499. doi: 10.1016/j.ymthe.2022.01.009. Epub 2022 Jan 7. Mol Ther. 2022. PMID: 35007758 Free PMC article.
Lentiviral delivery of the human wild-type tau protein mediates a slow and progressive neurodegenerative tau pathology in the rat brain.
Caillierez R, Bégard S, Lécolle K, Deramecourt V, Zommer N, Dujardin S, Loyens A, Dufour N, Aurégan G, Winderickx J, Hantraye P, Déglon N, Buée L, Colin M. Caillierez R, et al. Among authors: loyens a. Mol Ther. 2013 Jul;21(7):1358-68. doi: 10.1038/mt.2013.66. Epub 2013 Apr 23. Mol Ther. 2013. PMID: 23609018 Free PMC article.
Extracellular vesicles: Major actors of heterogeneity in tau spreading among human tauopathies.
Leroux E, Perbet R, Caillierez R, Richetin K, Lieger S, Espourteille J, Bouillet T, Bégard S, Danis C, Loyens A, Toni N, Déglon N, Deramecourt V, Schraen-Maschke S, Buée L, Colin M. Leroux E, et al. Among authors: loyens a. Mol Ther. 2022 Feb 2;30(2):782-797. doi: 10.1016/j.ymthe.2021.09.020. Epub 2021 Sep 24. Mol Ther. 2022. PMID: 34563677 Free PMC article.
Nuclear tau, a key player in neuronal DNA protection.
Sultan A, Nesslany F, Violet M, Bégard S, Loyens A, Talahari S, Mansuroglu Z, Marzin D, Sergeant N, Humez S, Colin M, Bonnefoy E, Buée L, Galas MC. Sultan A, et al. Among authors: loyens a. J Biol Chem. 2011 Feb 11;286(6):4566-75. doi: 10.1074/jbc.M110.199976. Epub 2010 Dec 3. J Biol Chem. 2011. PMID: 21131359 Free PMC article.
Ectosomes: a new mechanism for non-exosomal secretion of tau protein.
Dujardin S, Bégard S, Caillierez R, Lachaud C, Delattre L, Carrier S, Loyens A, Galas MC, Bousset L, Melki R, Aurégan G, Hantraye P, Brouillet E, Buée L, Colin M. Dujardin S, et al. Among authors: loyens a. PLoS One. 2014 Jun 27;9(6):e100760. doi: 10.1371/journal.pone.0100760. eCollection 2014. PLoS One. 2014. PMID: 24971751 Free PMC article.
Phosphorylation and O-GlcNAcylation of the PHF-1 Epitope of Tau Protein Induce Local Conformational Changes of the C-Terminus and Modulate Tau Self-Assembly Into Fibrillar Aggregates.
Cantrelle FX, Loyens A, Trivelli X, Reimann O, Despres C, Gandhi NS, Hackenberger CPR, Landrieu I, Smet-Nocca C. Cantrelle FX, et al. Among authors: loyens a. Front Mol Neurosci. 2021 Jun 17;14:661368. doi: 10.3389/fnmol.2021.661368. eCollection 2021. Front Mol Neurosci. 2021. PMID: 34220449 Free PMC article.
Sstr2A: a relevant target for the delivery of genes into human glioblastoma cells using fiber-modified adenoviral vectors.
Lécolle K, Bégard S, Caillierez R, Demeyer D, Grellier E, Loyens A, Csaba Z, Beauvillain JC, D'Halluin JC, Baroncini M, Lejeune JP, Sharif A, Prévot V, Dournaud P, Buée L, Colin M. Lécolle K, et al. Among authors: loyens a. Gene Ther. 2013 Mar;20(3):283-97. doi: 10.1038/gt.2012.39. Epub 2012 May 17. Gene Ther. 2013. PMID: 22592599
49 results