Hirao A - Search Results

1

SMURF2 phosphorylation at Thr249 modifies glioma stemness and tumorigenicity by regulating TGF-β receptor stability.

Hiraiwa M, Fukasawa K, Iezaki T, Sabit H, Horie T, Tokumura K, Iwahashi S, Murata M, Kobayashi M, Suzuki A, Park G, Kaneda K, Todo T, Hirao A, Nakada M, Hinoi E. Hiraiwa M, et al. Among authors: hirao a. Commun Biol. 2022 Jan 11;5(1):22. doi: 10.1038/s42003-021-02950-0. Commun Biol. 2022. PMID: 35017630 Free PMC article.

2

NKX2.2 suppresses self-renewal of glioma-initiating cells.

Muraguchi T, Tanaka S, Yamada D, Tamase A, Nakada M, Nakamura H, Hoshii T, Ooshio T, Tadokoro Y, Naka K, Ino Y, Todo T, Kuratsu J, Saya H, Hamada J, Hirao A. Muraguchi T, et al. Among authors: hirao a. Cancer Res. 2011 Feb 1;71(3):1135-45. doi: 10.1158/0008-5472.CAN-10-2304. Epub 2010 Dec 17. Cancer Res. 2011. PMID: 21169405

3

Combination therapy using Notch and Akt inhibitors is effective for suppressing invasion but not proliferation in glioma cells.

Jin R, Nakada M, Teng L, Furuta T, Sabit H, Hayashi Y, Demuth T, Hirao A, Sato H, Zhao G, Hamada J. Jin R, et al. Among authors: hirao a. Neurosci Lett. 2013 Feb 8;534:316-21. doi: 10.1016/j.neulet.2012.12.008. Epub 2012 Dec 20. Neurosci Lett. 2013. PMID: 23262078

4

Integrin α3 is overexpressed in glioma stem-like cells and promotes invasion.

Nakada M, Nambu E, Furuyama N, Yoshida Y, Takino T, Hayashi Y, Sato H, Sai Y, Tsuji T, Miyamoto KI, Hirao A, Hamada JI. Nakada M, et al. Among authors: hirao a. Br J Cancer. 2013 Jun 25;108(12):2516-24. doi: 10.1038/bjc.2013.218. Epub 2013 May 7. Br J Cancer. 2013. PMID: 23652300 Free PMC article.

5

Strong therapeutic potential of γ-secretase inhibitor MRK003 for CD44-high and CD133-low glioblastoma initiating cells.

Tanaka S, Nakada M, Yamada D, Nakano I, Todo T, Ino Y, Hoshii T, Tadokoro Y, Ohta K, Ali MA, Hayashi Y, Hamada J, Hirao A. Tanaka S, et al. Among authors: hirao a. J Neurooncol. 2015 Jan;121(2):239-50. doi: 10.1007/s11060-014-1630-z. Epub 2014 Oct 8. J Neurooncol. 2015. PMID: 25293440

6

Therapeutic Strategy for Targeting Aggressive Malignant Gliomas by Disrupting Their Energy Balance.

Hegazy AM, Yamada D, Kobayashi M, Kohno S, Ueno M, Ali MA, Ohta K, Tadokoro Y, Ino Y, Todo T, Soga T, Takahashi C, Hirao A. Hegazy AM, et al. Among authors: hirao a. J Biol Chem. 2016 Oct 7;291(41):21496-21509. doi: 10.1074/jbc.M116.734756. Epub 2016 Aug 12. J Biol Chem. 2016. PMID: 27519418 Free PMC article.

7

Identification of antipsychotic drug fluspirilene as a potential anti-glioma stem cell drug.

Dong Y, Furuta T, Sabit H, Kitabayashi T, Jiapaer S, Kobayashi M, Ino Y, Todo T, Teng L, Hirao A, Zhao SG, Nakada M. Dong Y, et al. Among authors: hirao a. Oncotarget. 2017 Dec 4;8(67):111728-111741. doi: 10.18632/oncotarget.22904. eCollection 2017 Dec 19. Oncotarget. 2017. PMID: 29340087 Free PMC article.

8

Autophagy inhibition synergizes with calcium mobilization to achieve efficient therapy of malignant gliomas.

Vu HT, Kobayashi M, Hegazy AM, Tadokoro Y, Ueno M, Kasahara A, Takase Y, Nomura N, Peng H, Ito C, Ino Y, Todo T, Nakada M, Hirao A. Vu HT, et al. Among authors: hirao a. Cancer Sci. 2018 Aug;109(8):2497-2508. doi: 10.1111/cas.13695. Epub 2018 Jul 26. Cancer Sci. 2018. PMID: 29902340 Free PMC article.

9

Identification of GSK3β inhibitor kenpaullone as a temozolomide enhancer against glioblastoma.

Kitabayashi T, Dong Y, Furuta T, Sabit H, Jiapaer S, Zhang J, Zhang G, Hayashi Y, Kobayashi M, Domoto T, Minamoto T, Hirao A, Nakada M. Kitabayashi T, et al. Among authors: hirao a. Sci Rep. 2019 Jul 11;9(1):10049. doi: 10.1038/s41598-019-46454-8. Sci Rep. 2019. PMID: 31296906 Free PMC article.

10

Identification of 2-Fluoropalmitic Acid as a Potential Therapeutic Agent Against Glioblastoma.

Jiapaer S, Furuta T, Dong Y, Kitabayashi T, Sabit H, Zhang J, Zhang G, Tanaka S, Kobayashi M, Hirao A, Nakada M. Jiapaer S, et al. Among authors: hirao a. Curr Pharm Des. 2020;26(36):4675-4684. doi: 10.2174/1381612826666200429092742. Curr Pharm Des. 2020. PMID: 32348209

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