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Antibodies elicited by SARS-CoV-2 infection or mRNA vaccines have reduced neutralizing activity against Beta and Omicron pseudoviruses.
Sievers BL, Chakraborty S, Xue Y, Gelbart T, Gonzalez JC, Cassidy AG, Golan Y, Prahl M, Gaw SL, Arunachalam PS, Blish CA, Boyd SD, Davis MM, Jagannathan P, Nadeau KC, Pulendran B, Singh U, Scheuermann RH, Frieman MB, Vashee S, Wang TT, Tan GS. Sievers BL, et al. Among authors: pulendran b. Sci Transl Med. 2022 Mar 2;14(634):eabn7842. doi: 10.1126/scitranslmed.abn7842. Epub 2022 Mar 2. Sci Transl Med. 2022. PMID: 35025672 Free PMC article.
Cell type discovery and representation in the era of high-content single cell phenotyping.
Bakken T, Cowell L, Aevermann BD, Novotny M, Hodge R, Miller JA, Lee A, Chang I, McCorrison J, Pulendran B, Qian Y, Schork NJ, Lasken RS, Lein ES, Scheuermann RH. Bakken T, et al. Among authors: pulendran b. BMC Bioinformatics. 2017 Dec 21;18(Suppl 17):559. doi: 10.1186/s12859-017-1977-1. BMC Bioinformatics. 2017. PMID: 29322913 Free PMC article.
T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers.
Arunachalam PS, Charles TP, Joag V, Bollimpelli VS, Scott MKD, Wimmers F, Burton SL, Labranche CC, Petitdemange C, Gangadhara S, Styles TM, Quarnstrom CF, Walter KA, Ketas TJ, Legere T, Jagadeesh Reddy PB, Kasturi SP, Tsai A, Yeung BZ, Gupta S, Tomai M, Vasilakos J, Shaw GM, Kang CY, Moore JP, Subramaniam S, Khatri P, Montefiori D, Kozlowski PA, Derdeyn CA, Hunter E, Masopust D, Amara RR, Pulendran B. Arunachalam PS, et al. Among authors: pulendran b. Nat Med. 2020 Jun;26(6):932-940. doi: 10.1038/s41591-020-0858-8. Epub 2020 May 11. Nat Med. 2020. PMID: 32393800 Free PMC article.
Adjuvanted H5N1 influenza vaccine enhances both cross-reactive memory B cell and strain-specific naive B cell responses in humans.
Ellebedy AH, Nachbagauer R, Jackson KJL, Dai YN, Han J, Alsoussi WB, Davis CW, Stadlbauer D, Rouphael N, Chromikova V, McCausland M, Chang CY, Cortese M, Bower M, Chennareddy C, Schmitz AJ, Zarnitsyna VI, Lai L, Rajabhathor A, Kazemian C, Antia R, Mulligan MJ, Ward AB, Fremont DH, Boyd SD, Pulendran B, Krammer F, Ahmed R. Ellebedy AH, et al. Among authors: pulendran b. Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):17957-17964. doi: 10.1073/pnas.1906613117. Epub 2020 Jul 13. Proc Natl Acad Sci U S A. 2020. PMID: 32661157 Free PMC article.
Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans.
Arunachalam PS, Wimmers F, Mok CKP, Perera RAPM, Scott M, Hagan T, Sigal N, Feng Y, Bristow L, Tak-Yin Tsang O, Wagh D, Coller J, Pellegrini KL, Kazmin D, Alaaeddine G, Leung WS, Chan JMC, Chik TSH, Choi CYC, Huerta C, Paine McCullough M, Lv H, Anderson E, Edupuganti S, Upadhyay AA, Bosinger SE, Maecker HT, Khatri P, Rouphael N, Peiris M, Pulendran B. Arunachalam PS, et al. Among authors: pulendran b. Science. 2020 Sep 4;369(6508):1210-1220. doi: 10.1126/science.abc6261. Epub 2020 Aug 11. Science. 2020. PMID: 32788292 Free PMC article.
The science and medicine of human immunology.
Pulendran B, Davis MM. Pulendran B, et al. Science. 2020 Sep 25;369(6511):eaay4014. doi: 10.1126/science.aay4014. Science. 2020. PMID: 32973003 Free PMC article. Review.
Injectable Hydrogels for Sustained Codelivery of Subunit Vaccines Enhance Humoral Immunity.
Roth GA, Gale EC, Alcántara-Hernández M, Luo W, Axpe E, Verma R, Yin Q, Yu AC, Lopez Hernandez H, Maikawa CL, Smith AAA, Davis MM, Pulendran B, Idoyaga J, Appel EA. Roth GA, et al. Among authors: pulendran b. ACS Cent Sci. 2020 Oct 28;6(10):1800-1812. doi: 10.1021/acscentsci.0c00732. Epub 2020 Sep 16. ACS Cent Sci. 2020. PMID: 33145416 Free PMC article.
The immunology of SARS-CoV-2 infections and vaccines.
Grigoryan L, Pulendran B. Grigoryan L, et al. Among authors: pulendran b. Semin Immunol. 2020 Aug;50:101422. doi: 10.1016/j.smim.2020.101422. Epub 2020 Nov 17. Semin Immunol. 2020. PMID: 33262067 Free PMC article. Review.
The C3/465 glycan hole cluster in BG505 HIV-1 envelope is the major neutralizing target involved in preventing mucosal SHIV infection.
Charles TP, Burton SL, Arunachalam PS, Cottrell CA, Sewall LM, Bollimpelli VS, Gangadhara S, Dey AK, Ward AB, Shaw GM, Hunter E, Amara RR, Pulendran B, van Gils MJ, Derdeyn CA. Charles TP, et al. Among authors: pulendran b. PLoS Pathog. 2021 Feb 8;17(2):e1009257. doi: 10.1371/journal.ppat.1009257. eCollection 2021 Feb. PLoS Pathog. 2021. PMID: 33556148 Free PMC article.
A system-view of Bordetella pertussis booster vaccine responses in adults primed with whole-cell versus acellular vaccine in infancy.
da Silva Antunes R, Soldevila F, Pomaznoy M, Babor M, Bennett J, Tian Y, Khalil N, Qian Y, Mandava A, Scheuermann RH, Cortese M, Pulendran B, Petro CD, Gilkes AP, Purcell LA, Sette A, Peters B. da Silva Antunes R, et al. Among authors: pulendran b. JCI Insight. 2021 Apr 8;6(7):e141023. doi: 10.1172/jci.insight.141023. JCI Insight. 2021. PMID: 33690224 Free PMC article.
272 results