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RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state.
Belenguer G, Mastrogiovanni G, Pacini C, Hall Z, Dowbaj AM, Arnes-Benito R, Sljukic A, Prior N, Kakava S, Bradshaw CR, Davies S, Vacca M, Saeb-Parsy K, Koo BK, Huch M. Belenguer G, et al. Among authors: bradshaw cr. Nat Commun. 2022 Jan 17;13(1):334. doi: 10.1038/s41467-021-27923-z. Nat Commun. 2022. PMID: 35039505 Free PMC article.
Human primary liver cancer-derived organoid cultures for disease modeling and drug screening.
Broutier L, Mastrogiovanni G, Verstegen MM, Francies HE, Gavarró LM, Bradshaw CR, Allen GE, Arnes-Benito R, Sidorova O, Gaspersz MP, Georgakopoulos N, Koo BK, Dietmann S, Davies SE, Praseedom RK, Lieshout R, IJzermans JNM, Wigmore SJ, Saeb-Parsy K, Garnett MJ, van der Laan LJ, Huch M. Broutier L, et al. Among authors: bradshaw cr. Nat Med. 2017 Dec;23(12):1424-1435. doi: 10.1038/nm.4438. Epub 2017 Nov 13. Nat Med. 2017. PMID: 29131160 Free PMC article.
Mechanical cell competition kills cells via induction of lethal p53 levels.
Wagstaff L, Goschorska M, Kozyrska K, Duclos G, Kucinski I, Chessel A, Hampton-O'Neil L, Bradshaw CR, Allen GE, Rawlins EL, Silberzan P, Carazo Salas RE, Piddini E. Wagstaff L, et al. Among authors: bradshaw cr. Nat Commun. 2016 Apr 25;7:11373. doi: 10.1038/ncomms11373. Nat Commun. 2016. PMID: 27109213 Free PMC article.
Epigenetic homogeneity in histone methylation underlies sperm programming for embryonic transcription.
Oikawa M, Simeone A, Hormanseder E, Teperek M, Gaggioli V, O'Doherty A, Falk E, Sporniak M, D'Santos C, Franklin VNR, Kishore K, Bradshaw CR, Keane D, Freour T, David L, Grzybowski AT, Ruthenburg AJ, Gurdon J, Jullien J. Oikawa M, et al. Among authors: bradshaw cr. Nat Commun. 2020 Jul 13;11(1):3491. doi: 10.1038/s41467-020-17238-w. Nat Commun. 2020. PMID: 32661239 Free PMC article.
34 results