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Targeting Cholesterol Biosynthesis with Statins Synergizes with AKT Inhibitors in Triple-Negative Breast Cancer.
Hillis AL, Martin TD, Manchester HE, Högström J, Zhang N, Lecky E, Kozlova N, Lee J, Persky NS, Root DE, Brown M, Cichowski K, Elledge SJ, Muranen T, Fruman DA, Barry ST, Clohessy JG, Madsen RR, Toker A. Hillis AL, et al. Among authors: hogstrom j. Cancer Res. 2024 Oct 1;84(19):3250-3266. doi: 10.1158/0008-5472.CAN-24-0970. Cancer Res. 2024. PMID: 39024548 Free PMC article.
Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-β.
Wiener Z, Band AM, Kallio P, Högström J, Hyvönen V, Kaijalainen S, Ritvos O, Haglund C, Kruuna O, Robine S, Louvard D, Ben-Neriah Y, Alitalo K. Wiener Z, et al. Among authors: hogstrom j. Proc Natl Acad Sci U S A. 2014 May 27;111(21):E2229-36. doi: 10.1073/pnas.1406444111. Epub 2014 May 13. Proc Natl Acad Sci U S A. 2014. PMID: 24825889 Free PMC article.
Expression of R-Spondin 1 in ApcMin/+ Mice Suppresses Growth of Intestinal Adenomas by Altering Wnt and Transforming Growth Factor Beta Signaling.
Lähde M, Heino S, Högström J, Kaijalainen S, Anisimov A, Flanagan D, Kallio P, Leppänen VM, Ristimäki A, Ritvos O, Wu K, Tammela T, Hodder M, Sansom OJ, Alitalo K. Lähde M, et al. Among authors: hogstrom j. Gastroenterology. 2021 Jan;160(1):245-259. doi: 10.1053/j.gastro.2020.09.011. Epub 2020 Sep 14. Gastroenterology. 2021. PMID: 32941878 Free article.
Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas.
Heino S, Fang S, Lähde M, Högström J, Nassiri S, Campbell A, Flanagan D, Raven A, Hodder M, Nasreddin N, Xue HH, Delorenzi M, Leedham S, Petrova TV, Sansom O, Alitalo K. Heino S, et al. Among authors: hogstrom j. Sci Adv. 2021 Nov 19;7(47):eabj0512. doi: 10.1126/sciadv.abj0512. Epub 2021 Nov 17. Sci Adv. 2021. PMID: 34788095 Free PMC article.
46 results