Austin CA - Search Results

1

Disease-associated mutations in topoisomerase IIβ result in defective NK cells.

Broderick L, Clay GM, Blum RH, Liu Y, McVicar R, Papes F, Booshehri LM, Cowell IG, Austin CA, Putnam CD, Kaufman DS. Broderick L, et al. Among authors: austin ca. J Allergy Clin Immunol. 2022 Jun;149(6):2171-2176.e3. doi: 10.1016/j.jaci.2021.12.792. Epub 2022 Jan 19. J Allergy Clin Immunol. 2022. PMID: 35063500 Free article.

2

Self-association of chromo domain peptides.

Cowell IG, Austin CA. Cowell IG, et al. Among authors: austin ca. Biochim Biophys Acta. 1997 Feb 8;1337(2):198-206. doi: 10.1016/s0167-4838(96)00165-3. Biochim Biophys Acta. 1997. PMID: 9048896

3

Nuclear distribution of human DNA topoisomerase IIbeta: a nuclear targeting signal resides in the 116-residue C-terminal tail.

Cowell IG, Willmore E, Chalton D, Marsh KL, Jazrawi E, Fisher LM, Austin CA. Cowell IG, et al. Among authors: austin ca. Exp Cell Res. 1998 Sep 15;243(2):232-40. doi: 10.1006/excr.1998.4150. Exp Cell Res. 1998. PMID: 9743583

4

Human topoisomerase IIalpha and IIbeta interact with the C-terminal region of p53.

Cowell IG, Okorokov AL, Cutts SA, Padget K, Bell M, Milner J, Austin CA. Cowell IG, et al. Among authors: austin ca. Exp Cell Res. 2000 Feb 25;255(1):86-94. doi: 10.1006/excr.1999.4772. Exp Cell Res. 2000. PMID: 10666337

5

Differential selection of acridine resistance mutations in human DNA topoisomerase IIbeta is dependent on the acridine structure.

Leontiou C, Watters GP, Gilroy KL, Heslop P, Cowell IG, Craig K, Lightowlers RN, Lakey JH, Austin CA. Leontiou C, et al. Among authors: austin ca. Mol Pharmacol. 2007 Apr;71(4):1006-14. doi: 10.1124/mol.106.032953. Epub 2007 Jan 5. Mol Pharmacol. 2007. PMID: 17209120

6

gammaH2AX foci form preferentially in euchromatin after ionising-radiation.

Cowell IG, Sunter NJ, Singh PB, Austin CA, Durkacz BW, Tilby MJ. Cowell IG, et al. Among authors: austin ca. PLoS One. 2007 Oct 24;2(10):e1057. doi: 10.1371/journal.pone.0001057. PLoS One. 2007. PMID: 17957241 Free PMC article.

7

DNA-dependent protein kinase is a therapeutic target and an indicator of poor prognosis in B-cell chronic lymphocytic leukemia.

Willmore E, Elliott SL, Mainou-Fowler T, Summerfield GP, Jackson GH, O'Neill F, Lowe C, Carter A, Harris R, Pettitt AR, Cano-Soumillac C, Griffin RJ, Cowell IG, Austin CA, Durkacz BW. Willmore E, et al. Among authors: austin ca. Clin Cancer Res. 2008 Jun 15;14(12):3984-92. doi: 10.1158/1078-0432.CCR-07-5158. Clin Cancer Res. 2008. PMID: 18559621

8

NK314, a topoisomerase II inhibitor that specifically targets the alpha isoform.

Toyoda E, Kagaya S, Cowell IG, Kurosawa A, Kamoshita K, Nishikawa K, Iiizumi S, Koyama H, Austin CA, Adachi N. Toyoda E, et al. Among authors: austin ca. J Biol Chem. 2008 Aug 29;283(35):23711-20. doi: 10.1074/jbc.M803936200. Epub 2008 Jul 2. J Biol Chem. 2008. PMID: 18596031 Free PMC article.

9

Role of Topoisomerase IIβ in DNA Damage Response following IR and Etoposide.

Sunter NJ, Cowell IG, Willmore E, Watters GP, Austin CA. Sunter NJ, et al. Among authors: austin ca. J Nucleic Acids. 2010 Aug 19;2010:710589. doi: 10.4061/2010/710589. J Nucleic Acids. 2010. PMID: 20847952 Free PMC article.

10

An overview of the visualisation and quantitation of low and high MW DNA adducts using the trapped in agarose DNA immunostaining (TARDIS) assay.

Cowell IG, Tilby MJ, Austin CA. Cowell IG, et al. Among authors: austin ca. Mutagenesis. 2011 Mar;26(2):253-60. doi: 10.1093/mutage/geq094. Epub 2010 Nov 10. Mutagenesis. 2011. PMID: 21068206 Review.

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