Wang J - Search Results

1

One-Pot Enzymatic Synthesis and Biological Evaluation of Ganglioside GM3 Derivatives as Potential Cancer Immunotherapeutics.

Wang J, Lu D, Sun R, Lei S, Luo S, Dang X, Zhang Y, Yuan C, Zhang Y, Wu J, Yang G, Fu L, Jiang F. Wang J, et al. J Med Chem. 2022 Feb 10;65(3):1883-1897. doi: 10.1021/acs.jmedchem.1c01301. Epub 2022 Jan 24. J Med Chem. 2022. PMID: 35073068

2

Surrogating and redirection of pyrazolo[1,5-a]pyrimidin-7(4H)-one core, a novel class of potent and selective DPP-4 inhibitors.

Deng X, Shen J, Zhu H, Xiao J, Sun R, Xie F, Lam C, Wang J, Qiao Y, Tavallaie MS, Hu Y, Du Y, Li J, Fu L, Jiang F. Deng X, et al. Among authors: wang j. Bioorg Med Chem. 2018 Feb 15;26(4):903-912. doi: 10.1016/j.bmc.2018.01.006. Epub 2018 Jan 10. Bioorg Med Chem. 2018. PMID: 29373269

3

Anti-diabetic potential of Pueraria lobata root extract through promoting insulin signaling by PTP1B inhibition.

Sun R, Deng X, Zhang D, Xie F, Wang D, Wang J, Tavallaie MS, Jiang F, Fu L. Sun R, et al. Among authors: wang j, wang d. Bioorg Chem. 2019 Jun;87:12-15. doi: 10.1016/j.bioorg.2019.02.046. Epub 2019 Feb 22. Bioorg Chem. 2019. PMID: 30852232

4

Drug discovery approaches targeting the incretin pathway.

Deng X, Tavallaie MS, Sun R, Wang J, Cai Q, Shen J, Lei S, Fu L, Jiang F. Deng X, et al. Among authors: wang j. Bioorg Chem. 2020 Jun;99:103810. doi: 10.1016/j.bioorg.2020.103810. Epub 2020 Apr 2. Bioorg Chem. 2020. PMID: 32325333 Review.

5

Synthesis and biological evaluation of geniposide derivatives as potent and selective PTPlB inhibitors.

Lei S, Zhang D, Qi Y, Chowdhury SR, Sun R, Wang J, Du Y, Fu L, Jiang F. Lei S, et al. Among authors: wang j. Eur J Med Chem. 2020 Nov 1;205:112508. doi: 10.1016/j.ejmech.2020.112508. Epub 2020 Jul 19. Eur J Med Chem. 2020. PMID: 32738350

6

Structural optimization of pyrazolo[1,5-a]pyrimidine derivatives as potent and highly selective DPP-4 inhibitors.

Shen J, Deng X, Sun R, Tavallaie MS, Wang J, Cai Q, Lam C, Lei S, Fu L, Jiang F. Shen J, et al. Among authors: wang j. Eur J Med Chem. 2020 Dec 15;208:112850. doi: 10.1016/j.ejmech.2020.112850. Epub 2020 Sep 19. Eur J Med Chem. 2020. PMID: 32987315

7

Synthesis, biological evaluation and molecular modeling of benzofuran piperidine derivatives as Aβ antiaggregant.

Chowdhury SR, Gu J, Hu Y, Wang J, Lei S, Tavallaie MS, Lam C, Lu D, Jiang F, Fu L. Chowdhury SR, et al. Among authors: wang j. Eur J Med Chem. 2021 Oct 15;222:113541. doi: 10.1016/j.ejmech.2021.113541. Epub 2021 May 25. Eur J Med Chem. 2021. PMID: 34116326

8

Design, synthesis and biological evaluation of novel thiazole-derivatives as mitochondrial targeting inhibitors of cancer cells.

Dang X, Lei S, Luo S, Hu Y, Wang J, Zhang D, Lu D, Jiang F, Fu L. Dang X, et al. Among authors: wang j. Bioorg Chem. 2021 Sep;114:105015. doi: 10.1016/j.bioorg.2021.105015. Epub 2021 May 25. Bioorg Chem. 2021. PMID: 34139611

9

Biological evaluation of mitochondria targeting small molecules as potent anticancer drugs.

Luo S, Dang X, Wang J, Yuan C, Hu Y, Lei S, Zhang Y, Lu D, Jiang F, Fu L. Luo S, et al. Among authors: wang j. Bioorg Chem. 2021 Sep;114:105055. doi: 10.1016/j.bioorg.2021.105055. Epub 2021 Jun 3. Bioorg Chem. 2021. PMID: 34144278

10

Discovery of Sortase A covalent inhibitors with benzofuranene cyanide structures as potential antibacterial agents against Staphylococcus aureus.

Lei S, Hu Y, Yuan C, Sun R, Wang J, Zhang Y, Zhang Y, Lu D, Fu L, Jiang F. Lei S, et al. Among authors: wang j. Eur J Med Chem. 2022 Feb 5;229:114032. doi: 10.1016/j.ejmech.2021.114032. Epub 2021 Dec 11. Eur J Med Chem. 2022. PMID: 34954590

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