Jenke R - Search Results

1

Balancing Histone Deacetylase (HDAC) Inhibition and Drug-likeness: Biological and Physicochemical Evaluation of Class I Selective HDAC Inhibitors.

Schäker-Hübner L, Haschemi R, Büch T, Kraft FB, Brumme B, Schöler A, Jenke R, Meiler J, Aigner A, Bendas G, Hansen FK. Schäker-Hübner L, et al. Among authors: jenke r. ChemMedChem. 2022 May 4;17(9):e202100755. doi: 10.1002/cmdc.202100755. Epub 2022 Feb 18. ChemMedChem. 2022. PMID: 35073610 Free PMC article.

2

Anticancer Therapy with HDAC Inhibitors: Mechanism-Based Combination Strategies and Future Perspectives.

Jenke R, Reßing N, Hansen FK, Aigner A, Büch T. Jenke R, et al. Cancers (Basel). 2021 Feb 5;13(4):634. doi: 10.3390/cancers13040634. Cancers (Basel). 2021. PMID: 33562653 Free PMC article. Review.

3

Inhibition of HER Receptors Reveals Distinct Mechanisms of Compensatory Upregulation of Other HER Family Members: Basis for Acquired Resistance and for Combination Therapy.

Gutsch D, Jenke R, Büch T, Aigner A. Gutsch D, et al. Among authors: jenke r. Cells. 2021 Jan 29;10(2):272. doi: 10.3390/cells10020272. Cells. 2021. PMID: 33572976 Free PMC article.

4

SATB1-Mediated Upregulation of the Oncogenic Receptor Tyrosine Kinase HER3 Antagonizes MET Inhibition in Gastric Cancer Cells.

Jenke R, Holzhäuser-Rein M, Mueller-Wilke S, Lordick F, Aigner A, Büch T. Jenke R, et al. Int J Mol Sci. 2020 Dec 23;22(1):82. doi: 10.3390/ijms22010082. Int J Mol Sci. 2020. PMID: 33374770 Free PMC article.

5

The HDAC Inhibitor Entinostat Mediates HER2 Downregulation in Gastric Cancer, Providing the Basis for Its Particular Efficacy in HER2 Amplified Tumors and in Combination Therapies.

Zenz T, Jenke R, Thieme R, Kahl T, Borchardt H, Gockel I, Hansen FK, Aigner A, Büch TR. Zenz T, et al. Among authors: jenke r. Cancer Res Treat. 2024 Dec 10. doi: 10.4143/crt.2024.546. Online ahead of print. Cancer Res Treat. 2024. PMID: 39668393 Free article.

6

Vorinostat Treatment of Gastric Cancer Cells Leads to ROS-Induced Cell Inhibition and a Complex Pattern of Molecular Alterations in Nrf2-Dependent Genes.

Lorenz L, Zenz T, Oliinyk D, Meier-Rosar F, Jenke R, Aigner A, Büch T. Lorenz L, et al. Among authors: jenke r. Pharmaceuticals (Basel). 2024 Aug 16;17(8):1080. doi: 10.3390/ph17081080. Pharmaceuticals (Basel). 2024. PMID: 39204185 Free PMC article.

7

HDAC inhibitors activate lipid peroxidation and ferroptosis in gastric cancer.

Jenke R, Oliinyk D, Zenz T, Körfer J, Schäker-Hübner L, Hansen FK, Lordick F, Meier-Rosar F, Aigner A, Büch T. Jenke R, et al. Biochem Pharmacol. 2024 Jul;225:116257. doi: 10.1016/j.bcp.2024.116257. Epub 2024 May 4. Biochem Pharmacol. 2024. PMID: 38705532 Free article.

8

Efficient polymeric nanoparticles for RNAi in macrophage reveal complex effects on polarization markers upon knockdown of STAT3/STAT6.

Walther M, Jenke R, Aigner A, Ewe A. Walther M, et al. Among authors: jenke r. Eur J Pharm Biopharm. 2024 Apr;197:114232. doi: 10.1016/j.ejpb.2024.114232. Epub 2024 Feb 22. Eur J Pharm Biopharm. 2024. PMID: 38395176 Free article.

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