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Selection analysis identifies unusual clustered mutational changes in Omicron lineage BA.1 that likely impact Spike function.
Martin DP, Lytras S, Lucaci AG, Maier W, Grüning B, Shank SD, Weaver S, MacLean OA, Orton RJ, Lemey P, Boni MF, Tegally H, Harkins G, Scheepers C, Bhiman JN, Everatt J, Amoako DG, San JE, Giandhari J, Sigal A; NGS-SA; Williamson C, Hsiao NY, von Gottberg A, De Klerk A, Shafer RW, Robertson DL, Wilkinson RJ, Sewell BT, Lessells R, Nekrutenko A, Greaney AJ, Starr TN, Bloom JD, Murrell B, Wilkinson E, Gupta RK, de Oliveira T, Kosakovsky Pond SL. Martin DP, et al. Among authors: de oliveira t, de klerk a. bioRxiv [Preprint]. 2022 Jan 18:2022.01.14.476382. doi: 10.1101/2022.01.14.476382. bioRxiv. 2022. Update in: Mol Biol Evol. 2022 Apr 11;39(4):msac061. doi: 10.1093/molbev/msac061 PMID: 35075456 Free PMC article. Updated. Preprint.
Modeling HIV-1 drug resistance as episodic directional selection.
Murrell B, de Oliveira T, Seebregts C, Kosakovsky Pond SL, Scheffler K; Southern African Treatment and Resistance Network-SATuRN Consortium. Murrell B, et al. Among authors: de oliveira t. PLoS Comput Biol. 2012;8(5):e1002507. doi: 10.1371/journal.pcbi.1002507. Epub 2012 May 10. PLoS Comput Biol. 2012. PMID: 22589711 Free PMC article.
Are subtype differences important in HIV drug resistance?
Lessells RJ, Katzenstein DK, de Oliveira T. Lessells RJ, et al. Among authors: de oliveira t. Curr Opin Virol. 2012 Oct;2(5):636-43. doi: 10.1016/j.coviro.2012.08.006. Epub 2012 Sep 21. Curr Opin Virol. 2012. PMID: 23006584 Free PMC article. Review.
High-levels of acquired drug resistance in adult patients failing first-line antiretroviral therapy in a rural HIV treatment programme in KwaZulu-Natal, South Africa.
Manasa J, Lessells RJ, Skingsley A, Naidu KK, Newell ML, McGrath N, de Oliveira T; Southern African Treatment and Resistance Network. Manasa J, et al. Among authors: de oliveira t. PLoS One. 2013 Aug 21;8(8):e72152. doi: 10.1371/journal.pone.0072152. eCollection 2013. PLoS One. 2013. PMID: 23991055 Free PMC article.
1,055 results