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Page 1
Coding variants identified in patients with diabetes alter PICK1 BAR domain function in insulin granule biogenesis.
Andersen RC, Schmidt JH, Rombach J, Lycas MD, Christensen NR, Lund VK, Stapleton DS, Pedersen SS, Olsen MA, Stoklund M, Noes-Holt G, Nielsen TT, Keller MP, Jansen AM, Herlo R, Pietropaolo M, Simonsen JB, Kjærulff O, Holst B, Attie AD, Gether U, Madsen KL. Andersen RC, et al. Among authors: lycas md. J Clin Invest. 2022 Mar 1;132(5):e144904. doi: 10.1172/JCI144904. J Clin Invest. 2022. PMID: 35077398 Free PMC article.
An Amphipathic Helix Directs Cellular Membrane Curvature Sensing and Function of the BAR Domain Protein PICK1.
Herlo R, Lund VK, Lycas MD, Jansen AM, Khelashvili G, Andersen RC, Bhatia V, Pedersen TS, Albornoz PBC, Johner N, Ammendrup-Johnsen I, Christensen NR, Erlendsson S, Stoklund M, Larsen JB, Weinstein H, Kjærulff O, Stamou D, Gether U, Madsen KL. Herlo R, et al. Among authors: lycas md. Cell Rep. 2018 May 15;23(7):2056-2069. doi: 10.1016/j.celrep.2018.04.074. Cell Rep. 2018. PMID: 29768204 Free article.
Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease.
Herborg F, Jensen KL, Tolstoy S, Arends NV, Posselt LP, Shekar A, Aguilar JI, Lund VK, Erreger K, Rickhag M, Lycas MD, Lonsdale MN, Rahbek-Clemmensen T, Sørensen AT, Newman AH, Løkkegaard A, Kjærulff O, Werge T; iPSYCH researchers; Møller LB, Matthies HJ, Galli A, Hjermind LE, Gether U. Herborg F, et al. Among authors: lycas md. JCI Insight. 2021 Sep 22;6(18):e151496. doi: 10.1172/jci.insight.151496. JCI Insight. 2021. PMID: 34375312 Free PMC article.
Disruption of the PDZ domain-binding motif of the dopamine transporter uniquely alters nanoscale distribution, dopamine homeostasis, and reward motivation.
Sørensen G, Rickhag M, Leo D, Lycas MD, Ridderstrøm PH, Weikop P, Lilja JH, Rifes P, Herborg F, Woldbye D, Wörtwein G, Gainetdinov RR, Fink-Jensen A, Gether U. Sørensen G, et al. Among authors: lycas md. J Biol Chem. 2021 Dec;297(6):101361. doi: 10.1016/j.jbc.2021.101361. Epub 2021 Oct 29. J Biol Chem. 2021. PMID: 34756883 Free PMC article.
Behavioral encoding across timescales by region-specific dopamine dynamics.
Jørgensen SH, Ejdrup AL, Lycas MD, Posselt LP, Madsen KL, Tian L, Dreyer JK, Herborg F, Sørensen AT, Gether U. Jørgensen SH, et al. Among authors: lycas md. Proc Natl Acad Sci U S A. 2023 Feb 14;120(7):e2215230120. doi: 10.1073/pnas.2215230120. Epub 2023 Feb 7. Proc Natl Acad Sci U S A. 2023. PMID: 36749722 Free PMC article.
21 results