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Page 1
Coding variants identified in patients with diabetes alter PICK1 BAR domain function in insulin granule biogenesis.
Andersen RC, Schmidt JH, Rombach J, Lycas MD, Christensen NR, Lund VK, Stapleton DS, Pedersen SS, Olsen MA, Stoklund M, Noes-Holt G, Nielsen TT, Keller MP, Jansen AM, Herlo R, Pietropaolo M, Simonsen JB, Kjærulff O, Holst B, Attie AD, Gether U, Madsen KL. Andersen RC, et al. Among authors: noes holt g. J Clin Invest. 2022 Mar 1;132(5):e144904. doi: 10.1172/JCI144904. J Clin Invest. 2022. PMID: 35077398 Free PMC article.
A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain.
Christensen NR, De Luca M, Lever MB, Richner M, Hansen AB, Noes-Holt G, Jensen KL, Rathje M, Jensen DB, Erlendsson S, Bartling CR, Ammendrup-Johnsen I, Pedersen SE, Schönauer M, Nissen KB, Midtgaard SR, Teilum K, Arleth L, Sørensen AT, Bach A, Strømgaard K, Meehan CF, Vaegter CB, Gether U, Madsen KL. Christensen NR, et al. Among authors: noes holt g. EMBO Mol Med. 2020 Jun 8;12(6):e11248. doi: 10.15252/emmm.201911248. Epub 2020 Apr 30. EMBO Mol Med. 2020. PMID: 32352640 Free PMC article.
A Novel Peripheral Action of PICK1 Inhibition in Inflammatory Pain.
Jensen KL, Noes-Holt G, Sørensen AT, Madsen KL. Jensen KL, et al. Among authors: noes holt g. Front Cell Neurosci. 2021 Dec 15;15:750902. doi: 10.3389/fncel.2021.750902. eCollection 2021. Front Cell Neurosci. 2021. PMID: 34975407 Free PMC article.
Systematic review and meta-analysis of cannabinoids, cannabis-based medicines, and endocannabinoid system modulators tested for antinociceptive effects in animal models of injury-related or pathological persistent pain.
Soliman N, Haroutounian S, Hohmann AG, Krane E, Liao J, Macleod M, Segelcke D, Sena C, Thomas J, Vollert J, Wever K, Alaverdyan H, Barakat A, Barthlow T, Bozer ALH, Davidson A, Diaz-delCastillo M, Dolgorukova A, Ferdousi MI, Healy C, Hong S, Hopkins M, James A, Leake HB, Malewicz NM, Mansfield M, Mardon AK, Mattimoe D, McLoone DP, Noes-Holt G, Pogatzki-Zahn EM, Power E, Pradier B, Romanos-Sirakis E, Segelcke A, Vinagre R, Yanes JA, Zhang J, Zhang XY, Finn DP, Rice ASC. Soliman N, et al. Among authors: noes holt g. Pain. 2021 Jul 1;162(Suppl 1):S26-S44. doi: 10.1097/j.pain.0000000000002269. Pain. 2021. PMID: 33729209 Free PMC article.
Peripherally restricted PICK1 inhibitor mPD5 ameliorates pain behaviors in murine inflammatory and neuropathic pain models.
Jensen KL, Christensen NR, Goddard CM, Jager SE, Noes-Holt G, Kanneworff IB, Jakobsen A, Jiménez-Fernández L, Peck EG, Sivertsen L, Comaposada Baro R, Houser GA, Mayer FP, Diaz-delCastillo M, Topp ML, Hopkins C, Thomsen CD, Soltan ABI, Tidemand FG, Arleth L, Heegaard AM, Sørensen AT, Madsen KL. Jensen KL, et al. Among authors: noes holt g. JCI Insight. 2024 Sep 17;9(20):e170976. doi: 10.1172/jci.insight.170976. JCI Insight. 2024. PMID: 39287978 Free PMC article.