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Target-Based Virtual Screening and LC/MS-Guided Isolation Procedure for Identifying Phloroglucinol-Terpenoid Inhibitors of SARS-CoV-2.
Hou B, Zhang YM, Liao HY, Fu LF, Li DD, Zhao X, Qi JX, Yang W, Xiao GF, Yang L, Zuo ZY, Wang L, Zhang XL, Bai F, Yang L, Gao GF, Song H, Hu JM, Shang WJ, Zhou J. Hou B, et al. Among authors: wang l. J Nat Prod. 2022 Feb 25;85(2):327-336. doi: 10.1021/acs.jnatprod.1c00805. Epub 2022 Jan 27. J Nat Prod. 2022. PMID: 35084181
Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors.
Jin Z, Du X, Xu Y, Deng Y, Liu M, Zhao Y, Zhang B, Li X, Zhang L, Peng C, Duan Y, Yu J, Wang L, Yang K, Liu F, Jiang R, Yang X, You T, Liu X, Yang X, Bai F, Liu H, Liu X, Guddat LW, Xu W, Xiao G, Qin C, Shi Z, Jiang H, Rao Z, Yang H. Jin Z, et al. Among authors: wang l. Nature. 2020 Jun;582(7811):289-293. doi: 10.1038/s41586-020-2223-y. Epub 2020 Apr 9. Nature. 2020. PMID: 32272481
Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein.
Wang L, Wu Y, Yao S, Ge H, Zhu Y, Chen K, Chen WZ, Zhang Y, Zhu W, Wang HY, Guo Y, Ma PX, Ren PX, Zhang XL, Li HQ, Ali MA, Xu WQ, Jiang HL, Zhang LK, Zhu LL, Ye Y, Shang WJ, Bai F. Wang L, et al. Among authors: wang hy. Acta Pharmacol Sin. 2022 Apr;43(4):788-796. doi: 10.1038/s41401-021-00735-z. Epub 2021 Aug 4. Acta Pharmacol Sin. 2022. PMID: 34349236 Free PMC article.
Immunological evaluation of an inactivated SARS-CoV-2 vaccine in rhesus macaques.
Chen H, Xie Z, Long R, Fan S, Li H, He Z, Xu K, Liao Y, Wang L, Zhang Y, Li X, Dong X, Mou T, Zhou X, Yang Y, Guo L, Yang J, Zheng H, Xu X, Li J, Liang Y, Li D, Zhao Z, Hong C, Zhao H, Jiang G, Che Y, Yang F, Hu Y, Wang X, Pu J, Ma K, Wang L, Cheng C, Duan W, Shen D, Zhao H, Jiang R, Deng X, Li Y, Zhu H, Zhou J, Yu L, Xu M, Yang H, Yi L, Zhou Z, Yang J, Duan N, Yang H, Zhao W, Yang W, Li C, Liu L, Li Q. Chen H, et al. Among authors: wang x, wang l. Mol Ther Methods Clin Dev. 2021 Dec 10;23:108-118. doi: 10.1016/j.omtm.2021.08.005. Epub 2021 Aug 26. Mol Ther Methods Clin Dev. 2021. PMID: 34462721 Free PMC article.
A glucose-like metabolite deficient in diabetes inhibits cellular entry of SARS-CoV-2.
Tong L, Xiao X, Li M, Fang S, Ma E, Yu X, Zhu Y, Wu C, Tian D, Yang F, Sun J, Qu J, Zheng N, Liao S, Tai W, Feng S, Zhang L, Li Y, Wang L, Han X, Sun S, Yang L, Zhong H, Zhao J, Liu W, Liu X, Wang P, Li L, Zhao G, Zhang R, Cheng G. Tong L, et al. Among authors: wang l, wang p. Nat Metab. 2022 May;4(5):547-558. doi: 10.1038/s42255-022-00567-z. Epub 2022 May 9. Nat Metab. 2022. PMID: 35534727
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