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Efficacy, durability, and safety of intravitreal faricimab with extended dosing up to every 16 weeks in patients with diabetic macular oedema (YOSEMITE and RHINE): two randomised, double-masked, phase 3 trials.
Wykoff CC, Abreu F, Adamis AP, Basu K, Eichenbaum DA, Haskova Z, Lin H, Loewenstein A, Mohan S, Pearce IA, Sakamoto T, Schlottmann PG, Silverman D, Sun JK, Wells JA, Willis JR, Tadayoni R; YOSEMITE and RHINE Investigators. Wykoff CC, et al. Among authors: sakamoto t. Lancet. 2022 Feb 19;399(10326):741-755. doi: 10.1016/S0140-6736(22)00018-6. Epub 2022 Jan 24. Lancet. 2022. PMID: 35085503 Clinical Trial.
Drug reflux during posterior subtenon infusion of triamcinolone acetonide in diffuse diabetic macular edema not only brings insufficient reduction but also causes elevation of intraocular pressure.
Shimura M, Yasuda K, Nakazawa T, Shiono T, Sakamoto T, Nishida K. Shimura M, et al. Among authors: sakamoto t. Graefes Arch Clin Exp Ophthalmol. 2009 Jul;247(7):907-12. doi: 10.1007/s00417-009-1074-x. Epub 2009 Apr 3. Graefes Arch Clin Exp Ophthalmol. 2009. PMID: 19343359
5,393 results