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Page 1
Aberrant upregulation of the glycolytic enzyme PFKFB3 in CLN7 neuronal ceroid lipofuscinosis.
Lopez-Fabuel I, Garcia-Macia M, Buondelmonte C, Burmistrova O, Bonora N, Alonso-Batan P, Morant-Ferrando B, Vicente-Gutierrez C, Jimenez-Blasco D, Quintana-Cabrera R, Fernandez E, Llop J, Ramos-Cabrer P, Sharaireh A, Guevara-Ferrer M, Fitzpatrick L, Thompton CD, McKay TR, Storch S, Medina DL, Mole SE, Fedichev PO, Almeida A, Bolaños JP. Lopez-Fabuel I, et al. Among authors: mckay tr. Nat Commun. 2022 Jan 27;13(1):536. doi: 10.1038/s41467-022-28191-1. Nat Commun. 2022. PMID: 35087090 Free PMC article.
NRF2 Orchestrates the Metabolic Shift during Induced Pluripotent Stem Cell Reprogramming.
Hawkins KE, Joy S, Delhove JM, Kotiadis VN, Fernandez E, Fitzpatrick LM, Whiteford JR, King PJ, Bolanos JP, Duchen MR, Waddington SN, McKay TR. Hawkins KE, et al. Among authors: mckay tr. Cell Rep. 2016 Mar 1;14(8):1883-91. doi: 10.1016/j.celrep.2016.02.003. Epub 2016 Feb 18. Cell Rep. 2016. PMID: 26904936 Free PMC article.
NF-κB Activity Initiates Human ESC-Derived Neural Progenitor Cell Differentiation by Inducing a Metabolic Maturation Program.
FitzPatrick LM, Hawkins KE, Delhove JMKM, Fernandez E, Soldati C, Bullen LF, Nohturfft A, Waddington SN, Medina DL, Bolaños JP, McKay TR. FitzPatrick LM, et al. Among authors: mckay tr. Stem Cell Reports. 2018 Jun 5;10(6):1766-1781. doi: 10.1016/j.stemcr.2018.03.015. Epub 2018 Apr 19. Stem Cell Reports. 2018. PMID: 29681545 Free PMC article.
Cellular models of Batten disease.
Minnis CJ, Thornton CD, FitzPatrick LM, McKay TR. Minnis CJ, et al. Among authors: mckay tr. Biochim Biophys Acta Mol Basis Dis. 2020 Sep 1;1866(9):165559. doi: 10.1016/j.bbadis.2019.165559. Epub 2019 Oct 23. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 31655107 Free PMC article. Review.
Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype.
Soldati C, Lopez-Fabuel I, Wanderlingh LG, Garcia-Macia M, Monfregola J, Esposito A, Napolitano G, Guevara-Ferrer M, Scotto Rosato A, Krogsaeter EK, Paquet D, Grimm CM, Montefusco S, Braulke T, Storch S, Mole SE, De Matteis MA, Ballabio A, Sampaio JL, McKay T, Johannes L, Bolaños JP, Medina DL. Soldati C, et al. EMBO Mol Med. 2021 Oct 7;13(10):e13742. doi: 10.15252/emmm.202013742. Epub 2021 Aug 19. EMBO Mol Med. 2021. PMID: 34411438 Free PMC article.
Safe and stable generation of induced pluripotent stem cells using doggybone DNA vectors.
Thornton CD, Fielding S, Karbowniczek K, Roig-Merino A, Burrows AE, FitzPatrick LM, Sharaireh A, Tite JP, Mole SE, Harbottle RP, Caproni LJ, McKay TR. Thornton CD, et al. Among authors: mckay tr. Mol Ther Methods Clin Dev. 2021 Oct 5;23:348-358. doi: 10.1016/j.omtm.2021.09.018. eCollection 2021 Dec 10. Mol Ther Methods Clin Dev. 2021. PMID: 34729381 Free PMC article.
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