Patel DJ - Search Results

1

The transcriptional regulator HDP1 controls expansion of the inner membrane complex during early sexual differentiation of malaria parasites.

Campelo Morillo RA, Tong X, Xie W, Abel S, Orchard LM, Daher W, Patel DJ, Llinás M, Le Roch KG, Kafsack BFC. Campelo Morillo RA, et al. Among authors: patel dj. Nat Microbiol. 2022 Feb;7(2):289-299. doi: 10.1038/s41564-021-01045-0. Epub 2022 Jan 27. Nat Microbiol. 2022. PMID: 35087229 Free PMC article.

2

Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.

Li H, Ilin S, Wang W, Duncan EM, Wysocka J, Allis CD, Patel DJ. Li H, et al. Among authors: patel dj. Nature. 2006 Jul 6;442(7098):91-5. doi: 10.1038/nature04802. Epub 2006 May 21. Nature. 2006. PMID: 16728978 Free PMC article.

3

Structure of the guide-strand-containing argonaute silencing complex.

Wang Y, Sheng G, Juranek S, Tuschl T, Patel DJ. Wang Y, et al. Among authors: patel dj. Nature. 2008 Nov 13;456(7219):209-13. doi: 10.1038/nature07315. Epub 2008 Aug 27. Nature. 2008. PMID: 18754009 Free PMC article.

4

Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1.

Law JA, Du J, Hale CJ, Feng S, Krajewski K, Palanca AM, Strahl BD, Patel DJ, Jacobsen SE. Law JA, et al. Among authors: patel dj. Nature. 2013 Jun 20;498(7454):385-9. doi: 10.1038/nature12178. Epub 2013 May 1. Nature. 2013. PMID: 23636332 Free PMC article.

5

A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.

Sun XJ, Wang Z, Wang L, Jiang Y, Kost N, Soong TD, Chen WY, Tang Z, Nakadai T, Elemento O, Fischle W, Melnick A, Patel DJ, Nimer SD, Roeder RG. Sun XJ, et al. Among authors: patel dj. Nature. 2013 Aug 1;500(7460):93-7. doi: 10.1038/nature12287. Epub 2013 Jun 30. Nature. 2013. PMID: 23812588 Free PMC article.

6

SRA- and SET-domain-containing proteins link RNA polymerase V occupancy to DNA methylation.

Johnson LM, Du J, Hale CJ, Bischof S, Feng S, Chodavarapu RK, Zhong X, Marson G, Pellegrini M, Segal DJ, Patel DJ, Jacobsen SE. Johnson LM, et al. Among authors: patel dj. Nature. 2014 Mar 6;507(7490):124-128. doi: 10.1038/nature12931. Epub 2014 Jan 22. Nature. 2014. PMID: 24463519 Free PMC article.

7

TRF2 binds branched DNA to safeguard telomere integrity.

Schmutz I, Timashev L, Xie W, Patel DJ, de Lange T. Schmutz I, et al. Among authors: patel dj. Nat Struct Mol Biol. 2017 Sep;24(9):734-742. doi: 10.1038/nsmb.3451. Epub 2017 Aug 14. Nat Struct Mol Biol. 2017. PMID: 28805810

8

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression.

Lama L, Adura C, Xie W, Tomita D, Kamei T, Kuryavyi V, Gogakos T, Steinberg JI, Miller M, Ramos-Espiritu L, Asano Y, Hashizume S, Aida J, Imaeda T, Okamoto R, Jennings AJ, Michino M, Kuroita T, Stamford A, Gao P, Meinke P, Glickman JF, Patel DJ, Tuschl T. Lama L, et al. Among authors: patel dj. Nat Commun. 2019 May 21;10(1):2261. doi: 10.1038/s41467-019-08620-4. Nat Commun. 2019. PMID: 31113940 Free PMC article.

9

Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation.

Xie W, Lama L, Adura C, Tomita D, Glickman JF, Tuschl T, Patel DJ. Xie W, et al. Among authors: patel dj. Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11946-11955. doi: 10.1073/pnas.1905013116. Epub 2019 May 29. Proc Natl Acad Sci U S A. 2019. PMID: 31142647 Free PMC article.

10

Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia.

Minuesa G, Albanese SK, Xie W, Kazansky Y, Worroll D, Chow A, Schurer A, Park SM, Rotsides CZ, Taggart J, Rizzi A, Naden LN, Chou T, Gourkanti S, Cappel D, Passarelli MC, Fairchild L, Adura C, Glickman JF, Schulman J, Famulare C, Patel M, Eibl JK, Ross GM, Bhattacharya S, Tan DS, Leslie CS, Beuming T, Patel DJ, Goldgur Y, Chodera JD, Kharas MG. Minuesa G, et al. Among authors: patel m, patel dj. Nat Commun. 2019 Jun 19;10(1):2691. doi: 10.1038/s41467-019-10523-3. Nat Commun. 2019. PMID: 31217428 Free PMC article.

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