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Page 1
TRF2 binds branched DNA to safeguard telomere integrity.
Schmutz I, Timashev L, Xie W, Patel DJ, de Lange T. Schmutz I, et al. Among authors: xie w. Nat Struct Mol Biol. 2017 Sep;24(9):734-742. doi: 10.1038/nsmb.3451. Epub 2017 Aug 14. Nat Struct Mol Biol. 2017. PMID: 28805810
Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression.
Lama L, Adura C, Xie W, Tomita D, Kamei T, Kuryavyi V, Gogakos T, Steinberg JI, Miller M, Ramos-Espiritu L, Asano Y, Hashizume S, Aida J, Imaeda T, Okamoto R, Jennings AJ, Michino M, Kuroita T, Stamford A, Gao P, Meinke P, Glickman JF, Patel DJ, Tuschl T. Lama L, et al. Among authors: xie w. Nat Commun. 2019 May 21;10(1):2261. doi: 10.1038/s41467-019-08620-4. Nat Commun. 2019. PMID: 31113940 Free PMC article.
Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia.
Minuesa G, Albanese SK, Xie W, Kazansky Y, Worroll D, Chow A, Schurer A, Park SM, Rotsides CZ, Taggart J, Rizzi A, Naden LN, Chou T, Gourkanti S, Cappel D, Passarelli MC, Fairchild L, Adura C, Glickman JF, Schulman J, Famulare C, Patel M, Eibl JK, Ross GM, Bhattacharya S, Tan DS, Leslie CS, Beuming T, Patel DJ, Goldgur Y, Chodera JD, Kharas MG. Minuesa G, et al. Among authors: xie w. Nat Commun. 2019 Jun 19;10(1):2691. doi: 10.1038/s41467-019-10523-3. Nat Commun. 2019. PMID: 31217428 Free PMC article.
The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation.
Batki J, Schnabl J, Wang J, Handler D, Andreev VI, Stieger CE, Novatchkova M, Lampersberger L, Kauneckaite K, Xie W, Mechtler K, Patel DJ, Brennecke J. Batki J, et al. Among authors: xie w. Nat Struct Mol Biol. 2019 Aug;26(8):720-731. doi: 10.1038/s41594-019-0270-6. Epub 2019 Aug 5. Nat Struct Mol Biol. 2019. PMID: 31384064 Free PMC article.
Structure-function analysis of microRNA 3'-end trimming by Nibbler.
Xie W, Sowemimo I, Hayashi R, Wang J, Burkard TR, Brennecke J, Ameres SL, Patel DJ. Xie W, et al. Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30370-30379. doi: 10.1073/pnas.2018156117. Epub 2020 Nov 16. Proc Natl Acad Sci U S A. 2020. PMID: 33199607 Free PMC article.
The Card1 nuclease provides defence during type III CRISPR immunity.
Rostøl JT, Xie W, Kuryavyi V, Maguin P, Kao K, Froom R, Patel DJ, Marraffini LA. Rostøl JT, et al. Among authors: xie w. Nature. 2021 Feb;590(7847):624-629. doi: 10.1038/s41586-021-03206-x. Epub 2021 Jan 18. Nature. 2021. PMID: 33461211 Free PMC article.
9,673 results