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Mutations that adapt SARS-CoV-2 to mink or ferret do not increase fitness in the human airway.
Zhou J, Peacock TP, Brown JC, Goldhill DH, Elrefaey AME, Penrice-Randal R, Cowton VM, De Lorenzo G, Furnon W, Harvey WT, Kugathasan R, Frise R, Baillon L, Lassaunière R, Thakur N, Gallo G, Goldswain H, Donovan-Banfield I, Dong X, Randle NP, Sweeney F, Glynn MC, Quantrill JL, McKay PF, Patel AH, Palmarini M, Hiscox JA, Bailey D, Barclay WS. Zhou J, et al. Among authors: mckay pf. Cell Rep. 2022 Feb 8;38(6):110344. doi: 10.1016/j.celrep.2022.110344. Epub 2022 Jan 19. Cell Rep. 2022. PMID: 35093235 Free PMC article.
A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS-CoV-2 infection model.
Peter AS, Roth E, Schulz SR, Fraedrich K, Steinmetz T, Damm D, Hauke M, Richel E, Mueller-Schmucker S, Habenicht K, Eberlein V, Issmail L, Uhlig N, Dolles S, Grüner E, Peterhoff D, Ciesek S, Hoffmann M, Pöhlmann S, McKay PF, Shattock RJ, Wölfel R, Socher E, Wagner R, Eichler J, Sticht H, Schuh W, Neipel F, Ensser A, Mielenz D, Tenbusch M, Winkler TH, Grunwald T, Überla K, Jäck HM. Peter AS, et al. Among authors: mckay pf. Eur J Immunol. 2022 May;52(5):770-783. doi: 10.1002/eji.202149374. Epub 2021 Sep 13. Eur J Immunol. 2022. PMID: 34355795 Free PMC article.
Detection and quantification of antibody to SARS CoV 2 receptor binding domain provides enhanced sensitivity, specificity and utility.
Rosadas C, Khan M, Parker E, Marchesin F, Katsanovskaja K, Sureda-Vives M, Fernandez N, Randell P, Harvey R, Lilley A, Harris BHL, Zuhair M, Fertleman M, Ijaz S, Dicks S, Short CE, Quinlan R, Taylor GP, Hu K, McKay P, Rosa A, Roustan C, Zuckerman M, El Bouzidi K, Cooke G, Flower B, Moshe M, Elliott P, Spencer AJ, Lambe T, Gilbert SC, Kingston H, Baillie JK, Openshaw PJM, Semple MG, Cherepanov P, McClure MO, Tedder RS; ISARIC4C Investigators. Rosadas C, et al. J Virol Methods. 2022 Apr;302:114475. doi: 10.1016/j.jviromet.2022.114475. Epub 2022 Jan 22. J Virol Methods. 2022. PMID: 35077719 Free PMC article.
Omicron breakthrough infections in vaccinated or previously infected hamsters.
Zhou J, Sukhova K, Peacock TP, McKay PF, Brown JC, Frise R, Baillon L, Moshe M, Kugathasan R, Shattock RJ, Barclay WS. Zhou J, et al. Among authors: mckay pf. Proc Natl Acad Sci U S A. 2023 Nov 7;120(45):e2308655120. doi: 10.1073/pnas.2308655120. Epub 2023 Oct 30. Proc Natl Acad Sci U S A. 2023. PMID: 37903249 Free PMC article.
Heterologous vaccination regimens with self-amplifying RNA and adenoviral COVID vaccines induce robust immune responses in mice.
Spencer AJ, McKay PF, Belij-Rammerstorfer S, Ulaszewska M, Bissett CD, Hu K, Samnuan K, Blakney AK, Wright D, Sharpe HR, Gilbride C, Truby A, Allen ER, Gilbert SC, Shattock RJ, Lambe T. Spencer AJ, et al. Among authors: mckay pf. Nat Commun. 2021 May 17;12(1):2893. doi: 10.1038/s41467-021-23173-1. Nat Commun. 2021. PMID: 34001897 Free PMC article.
Safety and immunogenicity of a self-amplifying RNA vaccine against COVID-19: COVAC1, a phase I, dose-ranging trial.
Pollock KM, Cheeseman HM, Szubert AJ, Libri V, Boffito M, Owen D, Bern H, O'Hara J, McFarlane LR, Lemm NM, McKay PF, Rampling T, Yim YTN, Milinkovic A, Kingsley C, Cole T, Fagerbrink S, Aban M, Tanaka M, Mehdipour S, Robbins A, Budd W, Faust SN, Hassanin H, Cosgrove CA, Winston A, Fidler S, Dunn DT, McCormack S, Shattock RJ; COVAC1 study Group. Pollock KM, et al. Among authors: mckay pf. EClinicalMedicine. 2022 Feb;44:101262. doi: 10.1016/j.eclinm.2021.101262. Epub 2022 Jan 14. EClinicalMedicine. 2022. PMID: 35043093 Free PMC article.
Rational Design of DNA-Expressed Stabilized Native-Like HIV-1 Envelope Trimers.
Aldon Y, McKay PF, Allen J, Ozorowski G, Felfödiné Lévai R, Tolazzi M, Rogers P, He L, de Val N, Fábián K, Scarlatti G, Zhu J, Ward AB, Crispin M, Shattock RJ. Aldon Y, et al. Among authors: mckay pf. Cell Rep. 2018 Sep 18;24(12):3324-3338.e5. doi: 10.1016/j.celrep.2018.08.051. Cell Rep. 2018. PMID: 30232012 Free PMC article.
104 results