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79 results

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A Phase Ib/II Randomized Study of RO4929097, a Gamma-Secretase or Notch Inhibitor with or without Vismodegib, a Hedgehog Inhibitor, in Advanced Sarcoma.
Gounder MM, Rosenbaum E, Wu N, Dickson MA, Sheikh TN, D'Angelo SP, Chi P, Keohan ML, Erinjeri JP, Antonescu CR, Agaram N, Hameed MR, Martindale M, Lefkowitz RA, Crago AM, Singer S, Tap WD, Takebe N, Qin LX, Schwartz GK. Gounder MM, et al. Among authors: keohan ml. Clin Cancer Res. 2022 Apr 14;28(8):1586-1594. doi: 10.1158/1078-0432.CCR-21-3874. Clin Cancer Res. 2022. PMID: 35110418 Free PMC article. Clinical Trial.
Multicenter phase II trial of sunitinib in the treatment of nongastrointestinal stromal tumor sarcomas.
George S, Merriam P, Maki RG, Van den Abbeele AD, Yap JT, Akhurst T, Harmon DC, Bhuchar G, O'Mara MM, D'Adamo DR, Morgan J, Schwartz GK, Wagner AJ, Butrynski JE, Demetri GD, Keohan ML. George S, et al. Among authors: keohan ml. J Clin Oncol. 2009 Jul 1;27(19):3154-60. doi: 10.1200/JCO.2008.20.9890. Epub 2009 May 18. J Clin Oncol. 2009. PMID: 19451429 Free PMC article. Clinical Trial.
Phase II study of sorafenib in patients with metastatic or recurrent sarcomas.
Maki RG, D'Adamo DR, Keohan ML, Saulle M, Schuetze SM, Undevia SD, Livingston MB, Cooney MM, Hensley ML, Mita MM, Takimoto CH, Kraft AS, Elias AD, Brockstein B, Blachère NE, Edgar MA, Schwartz LH, Qin LX, Antonescu CR, Schwartz GK. Maki RG, et al. Among authors: keohan ml. J Clin Oncol. 2009 Jul 1;27(19):3133-40. doi: 10.1200/JCO.2008.20.4495. Epub 2009 May 18. J Clin Oncol. 2009. PMID: 19451436 Free PMC article. Clinical Trial.
Activity of Sorafenib against desmoid tumor/deep fibromatosis.
Gounder MM, Lefkowitz RA, Keohan ML, D'Adamo DR, Hameed M, Antonescu CR, Singer S, Stout K, Ahn L, Maki RG. Gounder MM, et al. Among authors: keohan ml. Clin Cancer Res. 2011 Jun 15;17(12):4082-90. doi: 10.1158/1078-0432.CCR-10-3322. Epub 2011 Mar 29. Clin Cancer Res. 2011. PMID: 21447727 Free PMC article.
The cyclin-dependent kinase inhibitor flavopiridol potentiates doxorubicin efficacy in advanced sarcomas: preclinical investigations and results of a phase I dose-escalation clinical trial.
Luke JJ, D'Adamo DR, Dickson MA, Keohan ML, Carvajal RD, Maki RG, de Stanchina E, Musi E, Singer S, Schwartz GK. Luke JJ, et al. Among authors: keohan ml. Clin Cancer Res. 2012 May 1;18(9):2638-47. doi: 10.1158/1078-0432.CCR-11-3203. Epub 2012 Feb 28. Clin Cancer Res. 2012. PMID: 22374332 Free PMC article. Clinical Trial.
A Pilot Study of Anti-CTLA4 Antibody Ipilimumab in Patients with Synovial Sarcoma.
Maki RG, Jungbluth AA, Gnjatic S, Schwartz GK, D'Adamo DR, Keohan ML, Wagner MJ, Scheu K, Chiu R, Ritter E, Kachel J, Lowy I, Old LJ, Ritter G. Maki RG, et al. Among authors: keohan ml. Sarcoma. 2013;2013:168145. doi: 10.1155/2013/168145. Epub 2013 Feb 27. Sarcoma. 2013. PMID: 23554566 Free PMC article.
79 results