Parker MW - Search Results

1

Mechanism of Bloom syndrome complex assembly required for double Holliday junction dissolution and genome stability.

Hodson C, Low JKK, van Twest S, Jones SE, Swuec P, Murphy V, Tsukada K, Fawkes M, Bythell-Douglas R, Davies A, Holien JK, O'Rourke JJ, Parker BL, Glaser A, Parker MW, Mackay JP, Blackford AN, Costa A, Deans AJ. Hodson C, et al. Among authors: parker bl, parker mw. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2109093119. doi: 10.1073/pnas.2109093119. Proc Natl Acad Sci U S A. 2022. PMID: 35115399 Free PMC article.

2

Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling.

Polekhina G, House CM, Traficante N, Mackay JP, Relaix F, Sassoon DA, Parker MW, Bowtell DD. Polekhina G, et al. Among authors: parker mw. Nat Struct Biol. 2002 Jan;9(1):68-75. doi: 10.1038/nsb743. Nat Struct Biol. 2002. PMID: 11742346

3

Zanamivir-resistant influenza viruses with a novel neuraminidase mutation.

Hurt AC, Holien JK, Parker M, Kelso A, Barr IG. Hurt AC, et al. J Virol. 2009 Oct;83(20):10366-73. doi: 10.1128/JVI.01200-09. Epub 2009 Jul 29. J Virol. 2009. PMID: 19641000 Free PMC article.

4

Oseltamivir resistance and the H274Y neuraminidase mutation in seasonal, pandemic and highly pathogenic influenza viruses.

Hurt AC, Holien JK, Parker MW, Barr IG. Hurt AC, et al. Among authors: parker mw. Drugs. 2009;69(18):2523-31. doi: 10.2165/11531450-000000000-00000. Drugs. 2009. PMID: 19943705

5

Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobic packing point at the active site of insulin-regulated aminopeptidase.

Albiston AL, Pham V, Ye S, Ng L, Lew RA, Thompson PE, Holien JK, Morton CJ, Parker MW, Chai SY. Albiston AL, et al. Among authors: parker mw. Mol Pharmacol. 2010 Oct;78(4):600-7. doi: 10.1124/mol.110.065458. Epub 2010 Jul 13. Mol Pharmacol. 2010. PMID: 20628006

6

Direct involvement of the TEN domain at the active site of human telomerase.

Jurczyluk J, Nouwens AS, Holien JK, Adams TE, Lovrecz GO, Parker MW, Cohen SB, Bryan TM. Jurczyluk J, et al. Among authors: parker mw. Nucleic Acids Res. 2011 Mar;39(5):1774-88. doi: 10.1093/nar/gkq1083. Epub 2010 Nov 3. Nucleic Acids Res. 2011. PMID: 21051362 Free PMC article.

7

Identification and development of specific inhibitors for insulin-regulated aminopeptidase as a new class of cognitive enhancers.

Albiston AL, Diwakarla S, Fernando RN, Mountford SJ, Yeatman HR, Morgan B, Pham V, Holien JK, Parker MW, Thompson PE, Chai SY. Albiston AL, et al. Among authors: parker mw. Br J Pharmacol. 2011 Sep;164(1):37-47. doi: 10.1111/j.1476-5381.2011.01402.x. Br J Pharmacol. 2011. PMID: 21470200 Free PMC article. Review.

8

Amiloride is a competitive inhibitor of coxsackievirus B3 RNA polymerase.

Gazina EV, Smidansky ED, Holien JK, Harrison DN, Cromer BA, Arnold JJ, Parker MW, Cameron CE, Petrou S. Gazina EV, et al. Among authors: parker mw. J Virol. 2011 Oct;85(19):10364-74. doi: 10.1128/JVI.05022-11. Epub 2011 Jul 27. J Virol. 2011. PMID: 21795353 Free PMC article.

9

Structure of the lectin regulatory domain of the cholesterol-dependent cytolysin lectinolysin reveals the basis for its lewis antigen specificity.

Feil SC, Lawrence S, Mulhern TD, Holien JK, Hotze EM, Farrand S, Tweten RK, Parker MW. Feil SC, et al. Among authors: parker mw. Structure. 2012 Feb 8;20(2):248-58. doi: 10.1016/j.str.2011.11.017. Structure. 2012. PMID: 22325774 Free PMC article.

10

TRIM16 acts as an E3 ubiquitin ligase and can heterodimerize with other TRIM family members.

Bell JL, Malyukova A, Holien JK, Koach J, Parker MW, Kavallaris M, Marshall GM, Cheung BB. Bell JL, et al. Among authors: parker mw. PLoS One. 2012;7(5):e37470. doi: 10.1371/journal.pone.0037470. Epub 2012 May 21. PLoS One. 2012. PMID: 22629402 Free PMC article.

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