SCN5A mutation in Brugada syndrome is associated with substrate severity detected by electrocardiographic imaging and high-density electroanatomic mapping.
Pannone L, Monaco C, Sorgente A, Vergara P, Gauthey A, Calburean PA, Bisignani A, Paparella G, Ramak R, Overeinder I, Bala G, Almorad A, Ströker E, Pappaert G, Sieira J, Brugada P, Van Dooren S, de Ravel T, La Meir M, Chierchia GB, de Asmundis C.
Pannone L, et al. Among authors: brugada p.
Heart Rhythm. 2022 Jun;19(6):945-951. doi: 10.1016/j.hrthm.2022.01.034. Epub 2022 Feb 4.
Heart Rhythm. 2022.
PMID: 35124229
At baseline ECGI map, mean RVOT-RT was longer in SCN5A+ (P = .024). After ajmaline administration, SCN5A+ patients showed longer RVOT-AT (125.6 vs 100.8 ms; P = .045) and longer RVOT-RT (426.4 vs 397 ms; P = .033). After ajmaline administration, SCN5A+ showed …
At baseline ECGI map, mean RVOT-RT was longer in SCN5A+ (P = .024). After ajmaline administration, SCN5A+ patients showed longer RVOT …