Sears CL - Search Results

1

Comparative Analysis of Colon Cancer-Derived Fusobacterium nucleatum Subspecies: Inflammation and Colon Tumorigenesis in Murine Models.

Queen J, Domingue JC, White JR, Stevens C, Udayasuryan B, Nguyen TTD, Wu S, Ding H, Fan H, McMann M, Corona A, Larman TC, Verbridge SS, Housseau F, Slade DJ, Drewes JL, Sears CL. Queen J, et al. Among authors: sears cl. mBio. 2021 Feb 22;13(1):e0299121. doi: 10.1128/mbio.02991-21. Epub 2022 Feb 8. mBio. 2021. PMID: 35130731 Free PMC article.

2

Bacteroides fragilis toxin rearranges the actin cytoskeleton of HT29/C1 cells without direct proteolysis of actin or decrease in F-actin content.

Saidi RF, Jaeger K, Montrose MH, Wu S, Sears CL. Saidi RF, et al. Among authors: sears cl. Cell Motil Cytoskeleton. 1997;37(2):159-65. doi: 10.1002/(SICI)1097-0169(1997)37:2<159::AID-CM8>3.0.CO;2-3. Cell Motil Cytoskeleton. 1997. PMID: 9186013

3

Bacteroides fragilis enterotoxin cleaves the zonula adherens protein, E-cadherin.

Wu S, Lim KC, Huang J, Saidi RF, Sears CL. Wu S, et al. Among authors: sears cl. Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):14979-84. doi: 10.1073/pnas.95.25.14979. Proc Natl Acad Sci U S A. 1998. PMID: 9844001 Free PMC article.

4

Diversity of the metalloprotease toxin produced by enterotoxigenic Bacteroides fragilis.

Wu S, Dreyfus LA, Tzianabos AO, Hayashi C, Sears CL. Wu S, et al. Among authors: sears cl. Infect Immun. 2002 May;70(5):2463-71. doi: 10.1128/IAI.70.5.2463-2471.2002. Infect Immun. 2002. PMID: 11953383 Free PMC article.

5

Bacteroides fragilis enterotoxin induces c-Myc expression and cellular proliferation.

Wu S, Morin PJ, Maouyo D, Sears CL. Wu S, et al. Among authors: sears cl. Gastroenterology. 2003 Feb;124(2):392-400. doi: 10.1053/gast.2003.50047. Gastroenterology. 2003. PMID: 12557145

6

Bacteroides fragilis enterotoxin induces intestinal epithelial cell secretion of interleukin-8 through mitogen-activated protein kinases and a tyrosine kinase-regulated nuclear factor-kappaB pathway.

Wu S, Powell J, Mathioudakis N, Kane S, Fernandez E, Sears CL. Wu S, et al. Among authors: sears cl. Infect Immun. 2004 Oct;72(10):5832-9. doi: 10.1128/IAI.72.10.5832-5839.2004. Infect Immun. 2004. PMID: 15385484 Free PMC article.

7

The Bacteroides fragilis toxin binds to a specific intestinal epithelial cell receptor.

Wu S, Shin J, Zhang G, Cohen M, Franco A, Sears CL. Wu S, et al. Among authors: sears cl. Infect Immun. 2006 Sep;74(9):5382-90. doi: 10.1128/IAI.00060-06. Infect Immun. 2006. PMID: 16926433 Free PMC article.

8

Bacteroides fragilis toxin stimulates intestinal epithelial cell shedding and gamma-secretase-dependent E-cadherin cleavage.

Wu S, Rhee KJ, Zhang M, Franco A, Sears CL. Wu S, et al. Among authors: sears cl. J Cell Sci. 2007 Jun 1;120(Pt 11):1944-52. doi: 10.1242/jcs.03455. Epub 2007 May 15. J Cell Sci. 2007. PMID: 17504810 Free PMC article.

9

Enterotoxigenic bacteroides fragilis: a potential instigator of colitis.

Rabizadeh S, Rhee KJ, Wu S, Huso D, Gan CM, Golub JE, Wu X, Zhang M, Sears CL. Rabizadeh S, et al. Among authors: sears cl. Inflamm Bowel Dis. 2007 Dec;13(12):1475-83. doi: 10.1002/ibd.20265. Inflamm Bowel Dis. 2007. PMID: 17886290 Free PMC article.

10

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses.

Wu S, Rhee KJ, Albesiano E, Rabizadeh S, Wu X, Yen HR, Huso DL, Brancati FL, Wick E, McAllister F, Housseau F, Pardoll DM, Sears CL. Wu S, et al. Among authors: sears cl. Nat Med. 2009 Sep;15(9):1016-22. doi: 10.1038/nm.2015. Epub 2009 Aug 23. Nat Med. 2009. PMID: 19701202 Free PMC article.

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