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Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity.
Kadur Lakshminarasimha Murthy P, Xi R, Arguijo D, Everitt JI, Kocak DD, Kobayashi Y, Bozec A, Vicent S, Ding S, Crawford GE, Hsu D, Tata PR, Reddy T, Shen X. Kadur Lakshminarasimha Murthy P, et al. Among authors: hsu d. Dev Cell. 2022 Feb 7;57(3):310-328.e9. doi: 10.1016/j.devcel.2022.01.006. Dev Cell. 2022. PMID: 35134344 Free PMC article.
Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis.
Bu P, Chen KY, Xiang K, Johnson C, Crown SB, Rakhilin N, Ai Y, Wang L, Xi R, Astapova I, Han Y, Li J, Barth BB, Lu M, Gao Z, Mines R, Zhang L, Herman M, Hsu D, Zhang GF, Shen X. Bu P, et al. Among authors: hsu d. Cell Metab. 2018 Jun 5;27(6):1249-1262.e4. doi: 10.1016/j.cmet.2018.04.003. Epub 2018 Apr 26. Cell Metab. 2018. PMID: 29706565 Free PMC article.
A Comparative Oncology Drug Discovery Pipeline to Identify and Validate New Treatments for Osteosarcoma.
Somarelli JA, Rupprecht G, Altunel E, Flamant EM, Rao S, Sivaraj D, Lazarides AL, Hoskinson SM, Sheth MU, Cheng S, Kim SY, Ware KE, Agarwal A, Cullen MM, Selmic LE, Everitt JI, McCall SJ, Eward C, Eward WC, Hsu DS. Somarelli JA, et al. Among authors: hsu ds. Cancers (Basel). 2020 Nov 11;12(11):3335. doi: 10.3390/cancers12113335. Cancers (Basel). 2020. PMID: 33187254 Free PMC article.
Chromatin Remodeling of Colorectal Cancer Liver Metastasis is Mediated by an HGF-PU.1-DPP4 Axis.
Wang L, Wang E, Prado Balcazar J, Wu Z, Xiang K, Wang Y, Huang Q, Negrete M, Chen KY, Li W, Fu Y, Dohlman A, Mines R, Zhang L, Kobayashi Y, Chen T, Shi G, Shen JP, Kopetz S, Tata PR, Moreno V, Gersbach C, Crawford G, Hsu D, Huang E, Bu P, Shen X. Wang L, et al. Among authors: hsu d. Adv Sci (Weinh). 2021 Oct;8(19):e2004673. doi: 10.1002/advs.202004673. Epub 2021 Aug 10. Adv Sci (Weinh). 2021. PMID: 34378358 Free PMC article.
Patient-derived micro-organospheres enable clinical precision oncology.
Ding S, Hsu C, Wang Z, Natesh NR, Millen R, Negrete M, Giroux N, Rivera GO, Dohlman A, Bose S, Rotstein T, Spiller K, Yeung A, Sun Z, Jiang C, Xi R, Wilkin B, Randon PM, Williamson I, Nelson DA, Delubac D, Oh S, Rupprecht G, Isaacs J, Jia J, Chen C, Shen JP, Kopetz S, McCall S, Smith A, Gjorevski N, Walz AC, Antonia S, Marrer-Berger E, Clevers H, Hsu D, Shen X. Ding S, et al. Among authors: hsu d, hsu c. Cell Stem Cell. 2022 Jun 2;29(6):905-917.e6. doi: 10.1016/j.stem.2022.04.006. Epub 2022 May 3. Cell Stem Cell. 2022. PMID: 35508177 Free PMC article.
Rapid tissue prototyping with micro-organospheres.
Wang Z, Boretto M, Millen R, Natesh N, Reckzeh ES, Hsu C, Negrete M, Yao H, Quayle W, Heaton BE, Harding AT, Bose S, Driehuis E, Beumer J, Rivera GO, van Ineveld RL, Gex D, DeVilla J, Wang D, Puschhof J, Geurts MH, Yeung A, Hamele C, Smith A, Bankaitis E, Xiang K, Ding S, Nelson D, Delubac D, Rios A, Abi-Hachem R, Jang D, Goldstein BJ, Glass C, Heaton NS, Hsu D, Clevers H, Shen X. Wang Z, et al. Among authors: hsu d, hsu c. Stem Cell Reports. 2022 Sep 13;17(9):1959-1975. doi: 10.1016/j.stemcr.2022.07.016. Epub 2022 Aug 18. Stem Cell Reports. 2022. PMID: 35985334 Free PMC article.
Chromatin Remodeling in Patient-Derived Colorectal Cancer Models.
Xiang K, Wang E, Mantyh J, Rupprecht G, Negrete M, Sanati G, Hsu C, Randon P, Dohlman A, Kretzschmar K, Bose S, Giroux N, Ding S, Wang L, Balcazar JP, Huang Q, Sundaramoorthy P, Xi R, McCall SJ, Wang Z, Jiang C, Kang Y, Kopetz S, Crawford GE, Lipkin SM, Wang XF, Clevers H, Hsu D, Shen X. Xiang K, et al. Among authors: hsu d, hsu c. Adv Sci (Weinh). 2024 Apr;11(16):e2303379. doi: 10.1002/advs.202303379. Epub 2024 Feb 21. Adv Sci (Weinh). 2024. PMID: 38380561 Free PMC article.
miR-1269 promotes metastasis and forms a positive feedback loop with TGF-β.
Bu P, Wang L, Chen KY, Rakhilin N, Sun J, Closa A, Tung KL, King S, Kristine Varanko A, Xu Y, Huan Chen J, Zessin AS, Shealy J, Cummings B, Hsu D, Lipkin SM, Moreno V, Gümüş ZH, Shen X. Bu P, et al. Among authors: hsu d. Nat Commun. 2015 Apr 15;6:6879. doi: 10.1038/ncomms7879. Nat Commun. 2015. PMID: 25872451 Free PMC article.
1,456 results