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Page 1
Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation.
Kissel T, Ge C, Hafkenscheid L, Kwekkeboom JC, Slot LM, Cavallari M, He Y, van Schie KA, Vergroesen RD, Kampstra ASB, Reijm S, Stoeken-Rijsbergen G, Koeleman C, Voortman LM, Heitman LH, Xu B, Pruijn GJM, Wuhrer M, Rispens T, Huizinga TWJ, Scherer HU, Reth M, Holmdahl R, Toes REM. Kissel T, et al. Among authors: kwekkeboom jc. Sci Adv. 2022 Feb 11;8(6):eabm1759. doi: 10.1126/sciadv.abm1759. Epub 2022 Feb 9. Sci Adv. 2022. PMID: 35138894 Free PMC article.
The infrapatellar fat pad of patients with osteoarthritis has an inflammatory phenotype.
Klein-Wieringa IR, Kloppenburg M, Bastiaansen-Jenniskens YM, Yusuf E, Kwekkeboom JC, El-Bannoudi H, Nelissen RG, Zuurmond A, Stojanovic-Susulic V, Van Osch GJ, Toes RE, Ioan-Facsinay A. Klein-Wieringa IR, et al. Among authors: kwekkeboom jc. Ann Rheum Dis. 2011 May;70(5):851-7. doi: 10.1136/ard.2010.140046. Epub 2011 Jan 17. Ann Rheum Dis. 2011. PMID: 21242232
Adipocyte-derived lipids modulate CD4+ T-cell function.
Ioan-Facsinay A, Kwekkeboom JC, Westhoff S, Giera M, Rombouts Y, van Harmelen V, Huizinga TW, Deelder A, Kloppenburg M, Toes RE. Ioan-Facsinay A, et al. Among authors: kwekkeboom jc. Eur J Immunol. 2013 Jun;43(6):1578-87. doi: 10.1002/eji.201243096. Epub 2013 Apr 24. Eur J Immunol. 2013. PMID: 23504601 Free article.
Adipocytes modulate the phenotype of human macrophages through secreted lipids.
Klein-Wieringa IR, Andersen SN, Kwekkeboom JC, Giera M, de Lange-Brokaar BJ, van Osch GJ, Zuurmond AM, Stojanovic-Susulic V, Nelissen RG, Pijl H, Huizinga TW, Kloppenburg M, Toes RE, Ioan-Facsinay A. Klein-Wieringa IR, et al. Among authors: kwekkeboom jc. J Immunol. 2013 Aug 1;191(3):1356-63. doi: 10.4049/jimmunol.1203074. Epub 2013 Jul 1. J Immunol. 2013. PMID: 23817431
Are baseline high molecular weight adiponectin levels associated with radiographic progression in rheumatoid arthritis and osteoarthritis?
Klein-Wieringa IR, Andersen SN, Herb-van Toorn L, Kwekkeboom JC, van der Helm-van Mil AH, Meulenbelt I, Huizinga TW, Kloppenburg M, Toes RE, Ioan-Facsinay A. Klein-Wieringa IR, et al. Among authors: kwekkeboom jc. J Rheumatol. 2014 May;41(5):853-7. doi: 10.3899/jrheum.130888. Epub 2014 Apr 1. J Rheumatol. 2014. PMID: 24692529
Targeted lipidomics reveals activation of resolution pathways in knee osteoarthritis in humans.
Jónasdóttir HS, Brouwers H, Kwekkeboom JC, van der Linden HMJ, Huizinga T, Kloppenburg M, Toes REM, Giera M, Ioan-Facsinay A. Jónasdóttir HS, et al. Among authors: kwekkeboom jc. Osteoarthritis Cartilage. 2017 Jul;25(7):1150-1160. doi: 10.1016/j.joca.2017.01.018. Epub 2017 Feb 8. Osteoarthritis Cartilage. 2017. PMID: 28189826 Free article.
Antibodies and B cells recognising citrullinated proteins display a broad cross-reactivity towards other post-translational modifications.
Kissel T, Reijm S, Slot LM, Cavallari M, Wortel CM, Vergroesen RD, Stoeken-Rijsbergen G, Kwekkeboom JC, Kampstra A, Levarht E, Drijfhout JW, Bang H, Bonger KM, Janssen G, van Veelen PA, Huizinga T, Scherer HU, Reth M, Toes R. Kissel T, et al. Among authors: kwekkeboom jc. Ann Rheum Dis. 2020 Apr;79(4):472-480. doi: 10.1136/annrheumdis-2019-216499. Epub 2020 Feb 10. Ann Rheum Dis. 2020. PMID: 32041746
30 results