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Discovery of Covalent Inhibitors Targeting the Transcriptional Enhanced Associate Domain Central Pocket.
Karatas H, Akbarzadeh M, Adihou H, Hahne G, Pobbati AV, Yihui Ng E, Guéret SM, Sievers S, Pahl A, Metz M, Zinken S, Dötsch L, Nowak C, Thavam S, Friese A, Kang C, Hong W, Waldmann H. Karatas H, et al. Among authors: sievers s. J Med Chem. 2020 Oct 22;63(20):11972-11989. doi: 10.1021/acs.jmedchem.0c01275. Epub 2020 Oct 1. J Med Chem. 2020. PMID: 32907324 Free PMC article.
Cell-Based Identification of New IDO1 Modulator Chemotypes.
Hennes E, Lampe P, Dötsch L, Bruning N, Pulvermacher LM, Sievers S, Ziegler S, Waldmann H. Hennes E, et al. Among authors: sievers s. Angew Chem Int Ed Engl. 2021 Apr 26;60(18):9869-9874. doi: 10.1002/anie.202016004. Epub 2021 Mar 24. Angew Chem Int Ed Engl. 2021. PMID: 33565680 Free PMC article.
Identification of a Novel Pseudo-Natural Product Type IV IDO1 Inhibitor Chemotype.
Davies C, Dötsch L, Ciulla MG, Hennes E, Yoshida K, Gasper R, Scheel R, Sievers S, Strohmann C, Kumar K, Ziegler S, Waldmann H. Davies C, et al. Among authors: sievers s. Angew Chem Int Ed Engl. 2022 Oct 4;61(40):e202209374. doi: 10.1002/anie.202209374. Epub 2022 Aug 29. Angew Chem Int Ed Engl. 2022. PMID: 35959923 Free PMC article.
194 results