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Page 1
Three-dimensional colon cancer organoids model the response to CEA-CD3 T-cell engagers.
Teijeira A, Migueliz I, Garasa S, Karanikas V, Luri C, Cirella A, Olivera I, Cañamero M, Alvarez M, Ochoa MC, Rouzaut A, Rodriguez-Ruiz ME, Sanmamed MF, Klein C, Umaña P, Ponz M, Bacac M, Melero I. Teijeira A, et al. Among authors: cirella a. Theranostics. 2022 Jan 1;12(3):1373-1387. doi: 10.7150/thno.63359. eCollection 2022. Theranostics. 2022. PMID: 35154495 Free PMC article.
CD137 (4-1BB) requires physically associated cIAPs for signal transduction and antitumor effects.
Glez-Vaz J, Azpilikueta A, Ochoa MC, Olivera I, Gomis G, Cirella A, Luri-Rey C, Álvarez M, Pérez-Gracia JL, Ciordia S, Eguren-Santamaria I, Alexandru R, Berraondo P, de Andrea C, Teijeira Á, Corrales F, Zapata JM, Melero I. Glez-Vaz J, et al. Among authors: cirella a. Sci Adv. 2023 Aug 18;9(33):eadf6692. doi: 10.1126/sciadv.adf6692. Epub 2023 Aug 18. Sci Adv. 2023. PMID: 37595047 Free PMC article.
Known to recognize: a rare case of dyspnea.
Fontana A, Carducci P, Cirella A, Sinatti G, Balsano C. Fontana A, et al. Among authors: cirella a. Intern Emerg Med. 2024 Nov;19(8):2233-2235. doi: 10.1007/s11739-024-03654-z. Epub 2024 Jun 28. Intern Emerg Med. 2024. PMID: 38943035 No abstract available.
Interleukin-18 in cancer immunology and immunotherapy.
Cirella A, Olivera I, Luri-Rey C, Bolaños E, Berraondo P, Melero I. Cirella A, et al. Expert Opin Ther Targets. 2023 Jul-Dec;27(11):1035-1042. doi: 10.1080/14728222.2023.2287574. Epub 2023 Dec 7. Expert Opin Ther Targets. 2023. PMID: 37993172
Intraperitoneal administration of a modified vaccinia virus Ankara confers single-chain interleukin-12 expression to the omentum and achieves immune-mediated efficacy against peritoneal carcinomatosis.
Bella Á, Arrizabalaga L, Di Trani CA, Gonzalez-Gomariz J, Gomar C, Russo-Cabrera JS, Olivera I, Cirella A, Fernandez-Sendin M, Alvarez M, Teijeira A, Atay C, Medina-Echeverz J, Hinterberger M, Hochrein H, Melero I, Berraondo P, Aranda F. Bella Á, et al. Among authors: cirella a. J Immunother Cancer. 2023 Nov;11(11):e006702. doi: 10.1136/jitc-2023-006702. J Immunother Cancer. 2023. PMID: 37918917 Free PMC article.
Intratumoral co-injection of NK cells and NKG2A-neutralizing monoclonal antibodies.
Melero I, Ochoa MC, Molina C, Sanchez-Gregorio S, Garasa S, Luri-Rey C, Hervas-Stubbs S, Casares N, Elizalde E, Gomis G, Cirella A, Berraondo P, Teijeira A, Alvarez M. Melero I, et al. Among authors: cirella a. EMBO Mol Med. 2023 Nov 8;15(11):e17804. doi: 10.15252/emmm.202317804. Epub 2023 Oct 2. EMBO Mol Med. 2023. PMID: 37782273 Free PMC article.
Intratumoral immunotherapy with mRNAs encoding chimeric protein constructs encompassing IL-12, CD137 agonists, and TGF-β antagonists.
Cirella A, Bolaños E, Luri-Rey C, Di Trani CA, Olivera I, Gomis G, Glez-Vaz J, Pinci B, Garasa S, Sánchez-Gregorio S, Azpilikueta A, Eguren-Santamaria I, Valencia K, Palencia B, Alvarez M, Ochoa MC, Teijeira Á, Berraondo P, Melero I. Cirella A, et al. Mol Ther Nucleic Acids. 2023 Jul 28;33:668-682. doi: 10.1016/j.omtn.2023.07.026. eCollection 2023 Sep 12. Mol Ther Nucleic Acids. 2023. PMID: 37650116 Free PMC article.
Intratumoral injection of IL-12-encoding mRNA targeted to CSFR1 and PD-L1 exerts potent anti-tumor effects without substantial systemic exposure.
Di Trani CA, Cirella A, Arrizabalaga L, Alvarez M, Bella Á, Fernandez-Sendin M, Russo-Cabrera JS, Gomar C, Ardaiz N, Teijeira A, Bolaños E, González-Gomariz J, Otano I, Aranda F, Palencia B, Segués A, Huang S, van Duijnhoven SMJ, van Elsas A, Melero I, Berraondo P. Di Trani CA, et al. Among authors: cirella a. Mol Ther Nucleic Acids. 2023 Jul 19;33:599-616. doi: 10.1016/j.omtn.2023.07.020. eCollection 2023 Sep 12. Mol Ther Nucleic Acids. 2023. PMID: 37637207 Free PMC article.
Synergistic effects of combined immunotherapy strategies in a model of multifocal hepatocellular carcinoma.
Ochoa MC, Sanchez-Gregorio S, de Andrea CE, Garasa S, Alvarez M, Olivera I, Glez-Vaz J, Luri-Rey C, Etxeberria I, Cirella A, Azpilikueta A, Berraondo P, Argemi J, Sangro B, Teijeira A, Melero I. Ochoa MC, et al. Among authors: cirella a. Cell Rep Med. 2023 Apr 18;4(4):101009. doi: 10.1016/j.xcrm.2023.101009. Epub 2023 Apr 10. Cell Rep Med. 2023. PMID: 37040772 Free PMC article.
35 results