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Regulation of sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport in the cortico-striatal circuit.
Jaaro-Peled H, Kumar S, Hughes D, Sumitomo A, Kim SH, Zoubovsky S, Hirota-Tsuyada Y, Zala D, Bruyere J, Katz BM, Huang B, Flores R 3rd, Narayan S, Hou Z, Economides AN, Hikida T, Wetsel WC, Deisseroth K, Mori S, Brandon NJ, Tanaka M, Ishizuka K, Houslay MD, Saudou F, Dzirasa K, Sawa A, Tomoda T. Jaaro-Peled H, et al. Among authors: huang b. Mol Psychiatry. 2022 Mar;27(3):1805-1815. doi: 10.1038/s41380-021-01389-3. Epub 2022 Feb 14. Mol Psychiatry. 2022. PMID: 35165396 Free PMC article.
DISC1-dependent switch from progenitor proliferation to migration in the developing cortex.
Ishizuka K, Kamiya A, Oh EC, Kanki H, Seshadri S, Robinson JF, Murdoch H, Dunlop AJ, Kubo K, Furukori K, Huang B, Zeledon M, Hayashi-Takagi A, Okano H, Nakajima K, Houslay MD, Katsanis N, Sawa A. Ishizuka K, et al. Among authors: huang b. Nature. 2011 May 5;473(7345):92-6. doi: 10.1038/nature09859. Epub 2011 Apr 6. Nature. 2011. PMID: 21471969 Free PMC article.
Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits.
Niwa M, Kamiya A, Murai R, Kubo K, Gruber AJ, Tomita K, Lu L, Tomisato S, Jaaro-Peled H, Seshadri S, Hiyama H, Huang B, Kohda K, Noda Y, O'Donnell P, Nakajima K, Sawa A, Nabeshima T. Niwa M, et al. Among authors: huang b. Neuron. 2010 Feb 25;65(4):480-9. doi: 10.1016/j.neuron.2010.01.019. Neuron. 2010. PMID: 20188653 Free PMC article.
Drosophila modifier screens to identify novel neuropsychiatric drugs including aminergic agents for the possible treatment of Parkinson's disease and depression.
Lawal HO, Terrell A, Lam HA, Djapri C, Jang J, Hadi R, Roberts L, Shahi V, Chou MT, Biedermann T, Huang B, Lawless GM, Maidment NT, Krantz DE. Lawal HO, et al. Among authors: huang b. Mol Psychiatry. 2014 Feb;19(2):235-42. doi: 10.1038/mp.2012.170. Epub 2012 Dec 11. Mol Psychiatry. 2014. PMID: 23229049 Free PMC article.
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