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Regulation of sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport in the cortico-striatal circuit.
Jaaro-Peled H, Kumar S, Hughes D, Sumitomo A, Kim SH, Zoubovsky S, Hirota-Tsuyada Y, Zala D, Bruyere J, Katz BM, Huang B, Flores R 3rd, Narayan S, Hou Z, Economides AN, Hikida T, Wetsel WC, Deisseroth K, Mori S, Brandon NJ, Tanaka M, Ishizuka K, Houslay MD, Saudou F, Dzirasa K, Sawa A, Tomoda T. Jaaro-Peled H, et al. Among authors: tomoda t. Mol Psychiatry. 2022 Mar;27(3):1805-1815. doi: 10.1038/s41380-021-01389-3. Epub 2022 Feb 14. Mol Psychiatry. 2022. PMID: 35165396 Free PMC article.
DISC1 regulates trafficking and processing of APP and Aβ generation.
Shahani N, Seshadri S, Jaaro-Peled H, Ishizuka K, Hirota-Tsuyada Y, Wang Q, Koga M, Sedlak TW, Korth C, Brandon NJ, Kamiya A, Subramaniam S, Tomoda T, Sawa A. Shahani N, et al. Among authors: tomoda t. Mol Psychiatry. 2015 Jul;20(7):874-9. doi: 10.1038/mp.2014.100. Epub 2014 Sep 16. Mol Psychiatry. 2015. PMID: 25224257 Free PMC article.
Ulk2 controls cortical excitatory-inhibitory balance via autophagic regulation of p62 and GABAA receptor trafficking in pyramidal neurons.
Sumitomo A, Yukitake H, Hirai K, Horike K, Ueta K, Chung Y, Warabi E, Yanagawa T, Kitaoka S, Furuyashiki T, Narumiya S, Hirano T, Niwa M, Sibille E, Hikida T, Sakurai T, Ishizuka K, Sawa A, Tomoda T. Sumitomo A, et al. Among authors: tomoda t. Hum Mol Genet. 2018 Sep 15;27(18):3165-3176. doi: 10.1093/hmg/ddy219. Hum Mol Genet. 2018. PMID: 29893844 Free PMC article.
319 results