Silvestre S - Search Results

1

10β-Hydroxyestra-1,4-diene-3,17-dione as potential antiproliferative agent: in vitro biological evaluation and in silico studies.

Canário C, Matias M, Brito V, Cruz-Vicente P, Soeiro P, Santos AO, Falcão A, Silvestre S, Alves G. Canário C, et al. Among authors: silvestre s. Nat Prod Res. 2022 Dec;36(24):6459-6463. doi: 10.1080/14786419.2022.2039136. Epub 2022 Feb 15. Nat Prod Res. 2022. PMID: 35167416

2

HepaRG cell line as an in vitro model for screening drug-drug interactions mediated by metabolic induction: amiodarone used as a model substance.

Ferreira A, Rodrigues M, Silvestre S, Falcão A, Alves G. Ferreira A, et al. Among authors: silvestre s. Toxicol In Vitro. 2014 Dec;28(8):1531-5. doi: 10.1016/j.tiv.2014.08.004. Epub 2014 Aug 27. Toxicol In Vitro. 2014. PMID: 25172297

3

Effects of Hypericum perforatum extract and its main bioactive compounds on the cytotoxicity and expression of CYP1A2 and CYP2D6 in hepatic cells.

Silva SM, Martinho A, Moreno I, Silvestre S, Granadeiro LB, Alves G, Duarte AP, Domingues F, Gallardo E. Silva SM, et al. Among authors: silvestre s. Life Sci. 2016 Jan 1;144:30-6. doi: 10.1016/j.lfs.2015.11.004. Epub 2015 Nov 21. Life Sci. 2016. PMID: 26612349

4

Gastrodia elata and epilepsy: Rationale and therapeutic potential.

Matias M, Silvestre S, Falcão A, Alves G. Matias M, et al. Among authors: silvestre s. Phytomedicine. 2016 Nov 15;23(12):1511-1526. doi: 10.1016/j.phymed.2016.09.001. Epub 2016 Sep 5. Phytomedicine. 2016. PMID: 27765372 Review.

5

Recent Highlights on Molecular Hybrids Potentially Useful in Central Nervous System Disorders.

Matias M, Silvestre S, Falcao A, Alves G. Matias M, et al. Among authors: silvestre s. Mini Rev Med Chem. 2017;17(6):486-517. doi: 10.2174/1389557517666161111110121. Mini Rev Med Chem. 2017. PMID: 27834131 Review.

6

Early preclinical evaluation of dihydropyrimidin(thi)ones as potential anticonvulsant drug candidates.

Matias M, Campos G, Silvestre S, Falcão A, Alves G. Matias M, et al. Among authors: silvestre s. Eur J Pharm Sci. 2017 May 1;102:264-274. doi: 10.1016/j.ejps.2017.03.014. Epub 2017 Mar 15. Eur J Pharm Sci. 2017. PMID: 28315465

7

Novel 4-acetamide-2-alkylthio-N-acetanilides resembling nimesulide: Synthesis, cell viability evaluation and in silico studies.

Catarro M, Serrano J, Cavalheiro E, Ramos S, Santos AO, Silvestre S, Almeida P. Catarro M, et al. Among authors: silvestre s. Bioorg Med Chem. 2017 Aug 15;25(16):4304-4313. doi: 10.1016/j.bmc.2017.06.009. Epub 2017 Jun 16. Bioorg Med Chem. 2017. PMID: 28666860

8

Screening of pharmacokinetic properties of fifty dihydropyrimidin(thi)one derivatives using a combo of in vitro and in silico assays.

Matias M, Fortuna A, Bicker J, Silvestre S, Falcão A, Alves G. Matias M, et al. Among authors: silvestre s. Eur J Pharm Sci. 2017 Nov 15;109:334-346. doi: 10.1016/j.ejps.2017.08.023. Epub 2017 Aug 24. Eur J Pharm Sci. 2017. PMID: 28842351

9

Steroidal Oximes: Useful Compounds with Antitumor Activities.

Canario C, Silvestre S, Falcao A, Alves G. Canario C, et al. Among authors: silvestre s. Curr Med Chem. 2018 Feb 21;25(6):660-686. doi: 10.2174/0929867324666171003115400. Curr Med Chem. 2018. PMID: 28971759 Review.

10

Considerations and Pitfalls in Selecting the Drug Vehicles for Evaluation of New Drug Candidates: Focus on in vivo Pharmaco-Toxicological Assays Based on the Rotarod Performance Test.

Matias M, Silvestre S, Falcão A, Alves G. Matias M, et al. Among authors: silvestre s. J Pharm Pharm Sci. 2018;21(1):110-118. doi: 10.18433/jpps29656. J Pharm Pharm Sci. 2018. PMID: 29543586 Free article.

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