Karn J - Search Results

1

Impact of Tamoxifen on Vorinostat-Induced Human Immunodeficiency Virus Expression in Women on Antiretroviral Therapy: AIDS Clinical Trials Group A5366, The MOXIE Trial.

Scully EP, Aga E, Tsibris A, Archin N, Starr K, Ma Q, Morse GD, Squires KE, Howell BJ, Wu G, Hosey L, Sieg SF, Ehui L, Giguel F, Coxen K, Dobrowolski C, Gandhi M, Deeks S, Chomont N, Connick E, Godfrey C, Karn J, Kuritzkes DR, Bosch RJ, Gandhi RT. Scully EP, et al. Among authors: karn j. Clin Infect Dis. 2022 Oct 12;75(8):1389-1396. doi: 10.1093/cid/ciac136. Clin Infect Dis. 2022. PMID: 35176755 Free PMC article. Clinical Trial.

2

Epigenetic silencing of HIV-1 by the histone H3 lysine 27 methyltransferase enhancer of Zeste 2.

Friedman J, Cho WK, Chu CK, Keedy KS, Archin NM, Margolis DM, Karn J. Friedman J, et al. Among authors: karn j. J Virol. 2011 Sep;85(17):9078-89. doi: 10.1128/JVI.00836-11. Epub 2011 Jun 29. J Virol. 2011. PMID: 21715480 Free PMC article.

3

Methamphetamine activates nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and induces human immunodeficiency virus (HIV) transcription in human microglial cells.

Wires ES, Alvarez D, Dobrowolski C, Wang Y, Morales M, Karn J, Harvey BK. Wires ES, et al. Among authors: karn j. J Neurovirol. 2012 Oct;18(5):400-10. doi: 10.1007/s13365-012-0103-4. Epub 2012 May 22. J Neurovirol. 2012. PMID: 22618514 Free PMC article.

4

Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytes.

Mbonye UR, Gokulrangan G, Datt M, Dobrowolski C, Cooper M, Chance MR, Karn J. Mbonye UR, et al. Among authors: karn j. PLoS Pathog. 2013;9(5):e1003338. doi: 10.1371/journal.ppat.1003338. Epub 2013 May 2. PLoS Pathog. 2013. PMID: 23658523 Free PMC article. Clinical Trial.

5

Negative elongation factor is required for the maintenance of proviral latency but does not induce promoter-proximal pausing of RNA polymerase II on the HIV long terminal repeat.

Jadlowsky JK, Wong JY, Graham AC, Dobrowolski C, Devor RL, Adams MD, Fujinaga K, Karn J. Jadlowsky JK, et al. Among authors: karn j. Mol Cell Biol. 2014 Jun;34(11):1911-28. doi: 10.1128/MCB.01013-13. Epub 2014 Mar 17. Mol Cell Biol. 2014. PMID: 24636995 Free PMC article.

6

The histone deacetylase inhibitor vorinostat (SAHA) increases the susceptibility of uninfected CD4+ T cells to HIV by increasing the kinetics and efficiency of postentry viral events.

Lucera MB, Tilton CA, Mao H, Dobrowolski C, Tabler CO, Haqqani AA, Karn J, Tilton JC. Lucera MB, et al. Among authors: karn j. J Virol. 2014 Sep;88(18):10803-12. doi: 10.1128/JVI.00320-14. Epub 2014 Jul 9. J Virol. 2014. PMID: 25008921 Free PMC article.

7

Short chain fatty acids potently induce latent HIV-1 in T-cells by activating P-TEFb and multiple histone modifications.

Das B, Dobrowolski C, Shahir AM, Feng Z, Yu X, Sha J, Bissada NF, Weinberg A, Karn J, Ye F. Das B, et al. Among authors: karn j. Virology. 2015 Jan 1;474:65-81. doi: 10.1016/j.virol.2014.10.033. Epub 2014 Nov 14. Virology. 2015. PMID: 25463605 Free PMC article.

8

Novel high throughput pooled shRNA screening identifies NQO1 as a potential drug target for host directed therapy for tuberculosis.

Li Q, Karim AF, Ding X, Das B, Dobrowolski C, Gibson RM, Quiñones-Mateu ME, Karn J, Rojas RE. Li Q, et al. Among authors: karn j. Sci Rep. 2016 Jun 14;6:27566. doi: 10.1038/srep27566. Sci Rep. 2016. PMID: 27297123 Free PMC article.

9

Immortalization of primary microglia: a new platform to study HIV regulation in the central nervous system.

Garcia-Mesa Y, Jay TR, Checkley MA, Luttge B, Dobrowolski C, Valadkhan S, Landreth GE, Karn J, Alvarez-Carbonell D. Garcia-Mesa Y, et al. Among authors: karn j. J Neurovirol. 2017 Feb;23(1):47-66. doi: 10.1007/s13365-016-0499-3. Epub 2016 Nov 21. J Neurovirol. 2017. PMID: 27873219 Free PMC article.

10

Toll-like receptor 3 activation selectively reverses HIV latency in microglial cells.

Alvarez-Carbonell D, Garcia-Mesa Y, Milne S, Das B, Dobrowolski C, Rojas R, Karn J. Alvarez-Carbonell D, et al. Among authors: karn j. Retrovirology. 2017 Feb 6;14(1):9. doi: 10.1186/s12977-017-0335-8. Retrovirology. 2017. PMID: 28166799 Free PMC article.

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