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Genome-wide mapping of cancer dependency genes and genetic modifiers of chemotherapy in high-risk hepatoblastoma.
Fang J, Singh S, Cheng C, Natarajan S, Sheppard H, Abu-Zaid A, Durbin AD, Lee HW, Wu Q, Steele J, Connelly JP, Jin H, Chen W, Fan Y, Pruett-Miller SM, Rehg JE, Koo SC, Santiago T, Emmons J, Cairo S, Wang R, Glazer ES, Murphy AJ, Chen T, Davidoff AM, Armengol C, Easton J, Chen X, Yang J. Fang J, et al. Among authors: koo sc. Nat Commun. 2023 Jul 6;14(1):4003. doi: 10.1038/s41467-023-39717-6. Nat Commun. 2023. PMID: 37414763 Free PMC article.
An integrated single-cell RNA-seq map of human neuroblastoma tumors and preclinical models uncovers divergent mesenchymal-like gene expression programs.
Chapple RH, Liu X, Natarajan S, Alexander MIM, Kim Y, Patel AG, LaFlamme CW, Pan M, Wright WC, Lee HM, Zhang Y, Lu M, Koo SC, Long C, Harper J, Savage C, Johnson MD, Confer T, Akers WJ, Dyer MA, Sheppard H, Easton J, Geeleher P. Chapple RH, et al. Among authors: koo sc. Genome Biol. 2024 Jun 19;25(1):161. doi: 10.1186/s13059-024-03309-4. Genome Biol. 2024. PMID: 38898465 Free PMC article.
IL-18R supported CAR T cells targeting oncofetal tenascin C for the immunotherapy of pediatric sarcoma and brain tumors.
Wickman E, Lange S, Wagner J, Ibanez J, Tian L, Lu M, Sheppard H, Chiang J, Koo SC, Vogel P, Langfitt D, Perry SS, Shanmugam R, Bell M, Shaw TI, Krenciute G, Zhang J, Gottschalk S. Wickman E, et al. Among authors: koo sc. J Immunother Cancer. 2024 Nov 20;12(11):e009743. doi: 10.1136/jitc-2024-009743. J Immunother Cancer. 2024. PMID: 39572158 Free PMC article.
An integrated single-cell RNA-seq map of human neuroblastoma tumors and preclinical models uncovers divergent mesenchymal-like gene expression programs.
Chapple RH, Liu X, Natarajan S, Alexander MIM, Kim Y, Patel AG, LaFlamme CW, Pan M, Wright WC, Lee HM, Zhang Y, Lu M, Koo SC, Long C, Harper J, Savage C, Johnson MD, Confer T, Akers WJ, Dyer MA, Sheppard H, Easton J, Geeleher P. Chapple RH, et al. Among authors: koo sc. bioRxiv [Preprint]. 2024 Apr 22:2023.04.13.536639. doi: 10.1101/2023.04.13.536639. bioRxiv. 2024. Update in: Genome Biol. 2024 Jun 19;25(1):161. doi: 10.1186/s13059-024-03309-4 PMID: 38712039 Free PMC article. Updated. Preprint.
Discovery of immunotherapy targets for pediatric solid and brain tumors by exon-level expression.
Shaw TI, Wagner J, Tian L, Wickman E, Poudel S, Wang J, Paul R, Koo SC, Lu M, Sheppard H, Fan Y, O'Neil F, Lau CC, Zhou X, Zhang J, Gottschalk S. Shaw TI, et al. Among authors: koo sc. Res Sq [Preprint]. 2024 Jan 5:rs.3.rs-3821632. doi: 10.21203/rs.3.rs-3821632/v1. Res Sq. 2024. Update in: Nat Commun. 2024 May 3;15(1):3732. doi: 10.1038/s41467-024-47649-y PMID: 38260279 Free PMC article. Updated. Preprint.
Neonatal osteoblastic tumor with a novel PTBP1::FOSB fusion.
Blackburn PR, Douglass DP, Ramakrishnaiah RH, Montgomery CO, Shi Z, Wheeler DA, Koo SC. Blackburn PR, et al. Among authors: koo sc. Genes Chromosomes Cancer. 2023 Oct;62(10):611-616. doi: 10.1002/gcc.23149. Epub 2023 May 3. Genes Chromosomes Cancer. 2023. PMID: 37132513
85 results