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Discovery of a Partial Glucokinase Activator Clinical Candidate: Diethyl ((3-(3-((5-(Azetidine-1-carbonyl)pyrazin-2-yl)oxy)-5-isopropoxybenzamido)-1H-pyrazol-1-yl)methyl)phosphonate (BMS-820132).
Shi Y, Wang Y, Meng W, Brigance RP, Ryono DE, Bolton S, Zhang H, Chen S, Smirk R, Tao S, Tino JA, Williams KN, Sulsky R, Nielsen L, Ellsworth B, Wong MKY, Sun JH, Leith LW, Sun D, Wu DR, Gupta A, Rampulla R, Mathur A, Chen BC, Wang A, Fuentes-Catanio HG, Kunselman L, Cap M, Zalaznick J, Ma X, Liu H, Taylor JR, Zebo R, Jones B, Kalinowski S, Swartz J, Staal A, O'Malley K, Kopcho L, Muckelbauer JK, Krystek SR Jr, Spronk SA, Marcinkeviciene J, Everlof G, Chen XQ, Xu C, Li YX, Langish RA, Yang Y, Wang Q, Behnia K, Fura A, Janovitz EB, Pannacciulli N, Griffen S, Zinker BA, Krupinski J, Kirby M, Whaley J, Zahler R, Barrish JC, Robl JA, Cheng PTW. Shi Y, et al. Among authors: jones b. J Med Chem. 2022 Mar 10;65(5):4291-4317. doi: 10.1021/acs.jmedchem.1c02110. Epub 2022 Feb 18. J Med Chem. 2022. PMID: 35179904
2024 White paper on recent issues in bioanalysis: Impact of LDT in US and IVDR in EU; AI/ML for High Parameter Flow Cytometry; The rise of Olink Technology; CDx for AAV Gene Therapies; Integrative Bioanalysis by Multiple Platforms; Super Sensitive ADA/NAb LBA (PART 2A - Recommendations on Advanced Strategies for Biomarkers, IVD/CDx Assays (BAV), Cell Based Assays (CBA), and Ligand-Binding Assays (LBA) PART 2B - Regulatory Agencies' Input on Biomarkers, IVD/CDx, and Biomarker Assay Validation).
Bivi N, Graham D, Joglekar L, McGuire K, Stoop J, Zoghbi J, Baker B, Bandukwala A, Bond S, Buoninfante A, Chen J, Dysinger M, Engelbergs J, Fiscella M, Garofolo F, Hopper S, Jones B, King L, Murphy R, Palmer R, Sanderink G, Seyda A, Tang H, Van Tuyl A, Wagner L, Walravens K, Wang K, Zander H, Zhu L, Li M, Lin YD, Natalia M, Standifer N, Eck S, Goihberg P, Grugan K, Hedrick MN, Hopkins G, Kar S, Keller S, McGrath S, O'Gorman B, Stevens C, Stevens E, Terszowski G, Trampont PC, Yao S, Joyce A, Kumar S, Owen C, Pine S, Yearwood G, Cao L, Clausen V, Coble K, Culbert A, Gupta S, Hughes R, Liu S, Lu K, Martello R, Reese KJ, Stubenrauch KG, Wen Y. Bivi N, et al. Among authors: jones b. Bioanalysis. 2025 Jan 25:1-38. doi: 10.1080/17576180.2024.2442218. Online ahead of print. Bioanalysis. 2025. PMID: 39862107
Outpatient Low-Dose Initiation of Buprenorphine for People Using Fentanyl.
Suen LW, Chiang AY, Jones BLH, Soran CS, Geier M, Snyder HR, Neuhaus J, Myers JJ, Knight KR, Bazazi AR, Coffin PO. Suen LW, et al. Among authors: jones blh. JAMA Netw Open. 2025 Jan 2;8(1):e2456253. doi: 10.1001/jamanetworkopen.2024.56253. JAMA Netw Open. 2025. PMID: 39853975
Author Correction: Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids.
Gerli MFM, Calà G, Beesley MA, Sina B, Tullie L, Sun KY, Panariello F, Michielin F, Davidson JR, Russo FM, Jones BC, Lee DDH, Savvidis S, Xenakis T, Simcock IC, Straatman-Iwanowska AA, Hirst RA, David AL, O'Callaghan C, Olivo A, Eaton S, Loukogeorgakis SP, Cacchiarelli D, Deprest J, Li VSW, Giobbe GG, De Coppi P. Gerli MFM, et al. Among authors: jones bc. Nat Med. 2025 Jan 21. doi: 10.1038/s41591-025-03504-1. Online ahead of print. Nat Med. 2025. PMID: 39838120 No abstract available.
7,340 results